eBook Huntington Disease, 1st Edition

  • Andrew S. Feigin
  • Karen E. Anderson
  • Published By:
  • ISBN-10: 0128019034
  • ISBN-13: 9780128019030
  • DDC: 616.851
  • Grade Level Range: 11th Grade - College Senior
  • 312 Pages | eBook
  • Original Copyright 2017 | Published/Released May 2018
  • This publication's content originally published in print form: 2017
  • Price:  Sign in for price

About

Overview

This volume summarizes the most recent findings related to Huntington disease, providing both cutting edge coverage for clinical/research specialists looking to expand their knowledge base of Huntington disease information, as well as solid groundwork for advanced students from various backgrounds (neurology, psychiatry, neuropsychology, genetics). It includes all major areas of Huntington disease clinical care and research. This book also addresses behavioral and cognitive symptoms, brain imaging, and family dynamics and therapeutic alliances in working with individuals affected by HD. Clinical trials are covered extensively, including design considerations for therapeutic studies.

Table of Contents

Front Cover.
Half Title Page.
Half Title Page.
Title Page.
Copyright Page.
Handbook of Clinical Neurology 3rd Series.
Foreword.
Preface.
Contributors.
Contents.
Basic Science.
1: Genetics of Huntington Disease.
2: Mechanisms Underlying Neurodegeneration in Huntington Disease: Applications to Novel Disease-Modifying Therapies.
Clinical Aspects.
3: Epidemiology of Huntington Disease.
4: Statistical Modeling of Huntington Disease Onset.
5: The Diagnosis and Natural History of Huntington Disease.
6: Cognitive and Behavioral Changes in Huntington Disease Before Diagnosis.
7: Preclinical Motor Manifestations of Huntington Disease.
8: The Highly Anxious Individual Presenting for Huntington Disease-Predictive Genetic Testing: The Psychiatrist’s Role in Assessment and Counseling.
9: Preimplantation Genetics and Other Reproductive Options in Huntington Disease.
10: Genetic Testing for Huntington Disease.
Treatment of Huntington Disease.
11: Medical Treatment of Behavioral Manifestations of Huntington Disease.
12: Medical Management of Motor Manifestations of Huntington Disease.
13: The Role of Rehabilitation Therapy in Huntington Disease.
14: Contemporary Health Care for Huntington Disease.
15: The Impact of Huntington Disease on Young People.
16: Making a Measurable Difference in Advanced Huntington Disease Care.
Experimental Therapeutics.
17: New Symptomatic Therapies for Huntington Disease.
18: Motor Outcome Measures in Huntington Disease Clinical Trials.
19: Cognitive Assessment in Huntington Disease Clinical Drug Trials.
Biomarkers.
20: Structural Imaging in Premanifest and Manifest Huntington Disease.
21: Functional Imaging in Huntington Disease.
Index.