eBook Genes, Environment and Alzheimer's Disease, 1st Edition

  • Orly Lazarov
  • Giuseppina Tesco
  • Published By:
  • ISBN-10: 0128028858
  • ISBN-13: 9780128028858
  • DDC: 616.831042
  • Grade Level Range: College Freshman - College Senior
  • 448 Pages | eBook
  • Original Copyright 2016 | Published/Released August 2016
  • This publication's content originally published in print form: 2016
  • Price:  Sign in for price

About

Overview

This title is the first to thoroughly explore the link between genetic and environmental risk factors for Alzheimer’s disease and dementia. It also discusses how lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of AD. It is an excellent resource for basic and clinical neuroscientists.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
Contents.
List of Contributors.
Foreword.
Preface.
Dedication.
Introduction.
1: Molecular Mechanisms of Learning and Memory*.
2: When Cognitive Decline Becomes Pathology: From Normal Aging to Alzheimer's Disease.
3: Adult Neurogenesis and Cognitive Function: Relevance for Disorders Associated with Human Aging.
Hallmarks and Genetic Forms of AD.
4: The Amyloid β Precursor Protein and Cognitive Function in Alzheimer's Disease.
5: Molecular Pathways in Alzheimer's Disease and Cognitive Function: New Insights into Pathobiology of Tau.
Genetic and Environmental Risk Factors.
6: Apolipoprotein E and Amyloid-β-Independent Mechanisms in Alzheimer's Disease.
7: Lifestyle and Alzheimer's Disease: The Role of Environmental Factors in Disease Development.
8: Role of BACE1 in Cognitive Function, from Alzheimer's Disease to Traumatic Brain Injury.
9: Traumatic Brain Injury and Rationale for a Neuropsychological Diagnosis of Diffuse Axonal Injury.
10: Alzheimer's Disease and the Sleep–Wake Cycle.
11: Stroke, Cognitive Function, and Alzheimer's Disease.
12: Cerebral Innate Immunity: A New Conceptual Framework for Alzheimer's Disease.
13: Type 2 Diabetes Mellitus as a Risk Factor for Alzheimer's Disease.
Index.
Front Cover.
Half Title Page.
Title Page.
Copyright Page.
Contents.
List of Contributors.
Foreword.
Preface.
Dedication.
Introduction.
1: Molecular Mechanisms of Learning and Memory*.
2: When Cognitive Decline Becomes Pathology: From Normal Aging to Alzheimer's Disease.
3: Adult Neurogenesis and Cognitive Function: Relevance for Disorders Associated with Human Aging.
Hallmarks and Genetic Forms of AD.
4: The Amyloid β Precursor Protein and Cognitive Function in Alzheimer's Disease.
5: Molecular Pathways in Alzheimer's Disease and Cognitive Function: New Insights into Pathobiology of Tau.
Genetic and Environmental Risk Factors.
6: Apolipoprotein E and Amyloid-β-Independent Mechanisms in Alzheimer's Disease.
7: Lifestyle and Alzheimer's Disease: The Role of Environmental Factors in Disease Development.
8: Role of BACE1 in Cognitive Function, from Alzheimer's Disease to Traumatic Brain Injury.
9: Traumatic Brain Injury and Rationale for a Neuropsychological Diagnosis of Diffuse Axonal Injury.
10: Alzheimer's Disease and the Sleep–Wake Cycle.
11: Stroke, Cognitive Function, and Alzheimer's Disease.
12: Cerebral Innate Immunity: A New Conceptual Framework for Alzheimer's Disease.
13: Type 2 Diabetes Mellitus as a Risk Factor for Alzheimer's Disease.
Index.