Genetic Control of Malaria and Dengue, 1st Edition

  • Zach Adelman
  • Published By:
  • ISBN-10: 0128004053
  • ISBN-13: 9780128004050
  • DDC: 616.9362
  • Grade Level Range: 11th Grade - College Senior
  • 486 Pages | eBook
  • Original Copyright 2015 | Published/Released March 2016
  • This publication's content originally published in print form: 2015

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This book focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
List of Contributors.
1: Transgenic Pests and Human Health: A Short Overview of Social, Cultural, and Scientific Considerations*.
2: Concept and History of Genetic Control.
3: Considerations for Disrupting Malaria Transmission in Africa Using Genetically Modified Mosquitoes, Ecology of Anopheline Disease Vectors, and Current Methods of Control.
4: Ecology of Malaria Vectors and Current (Nongenetic) Methods of Control in the Asia Region.
5: Ecology of Anopheles darlingi, the Primary Malaria Vector in the Americas and Current Nongenetic Methods of Vector Control.
6: Considerations for Disrupting Dengue Virus Transmission; Ecology of Aedes aegypti and Current (Nongenetic) Methods of Control.
7: The Challenge of Disrupting Vectorial Capacity.
8: Gene Insertion and Deletion in Mosquitoes.
9: Gene Drive Strategies for Population Replacement.
10: Exploring the Sex-Determination Pathway for Control of Mosquito-Borne Infectious Diseases.
11: Disruption of Mosquito Olfaction.
12: Disruption of Mosquito Blood Meal Protein Metabolism.
13: Engineering Pathogen Resistance in Mosquitoes.
14: Genetic Control of Malaria and Dengue Using Wolbachia.
15: Employing the Mosquito Microflora for Disease Control.
16: Regulation of Transgenic Mosquitoes.
17: Economic Analysis of Genetically Modified Mosquito Strategies.
18: Community Engagement.
19: Impact of Genetic Modification of Vector Populations on the Malaria Eradication Agenda.