Biological Research on Addiction, 1st Edition

  • Published By:
  • ISBN-10: 0123983606
  • ISBN-13: 9780123983602
  • DDC: 616.86
  • Grade Level Range: College Freshman - College Senior
  • 758 Pages | eBook
  • Original Copyright 2013 | Published/Released June 2014
  • This publication's content originally published in print form: 2013

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Biological Research on Addiction examines the neurobiological mechanisms of drug use and drug addiction, describing how the brain responds to addictive substances as well as how it is affected by drugs of abuse. The book's four main sections examine behavioral and molecular biology; neuroscience; genetics; and neuroimaging and neuropharmacology as they relate to the addictive process. This volume is especially effective in presenting current knowledge on the key neurobiological and genetic elements in an individual's susceptibility to drug dependence, as well as the processes by which some individuals proceed from casual drug use to drug dependence. Biological Research on Addiction is one of three volumes comprising the 2,500-page series, Comprehensive Addictive Behaviors and Disorders. This series provides the most complete collection of current knowledge on addictive behaviors and disorders to date. In short, it is the definitive reference work on addictions.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
Editors: Biographies.
List of Contributors.
1: Behavioral Biology, Preclinical Animal Studies of Addiction.
2: Neurobiological Mechanisms of Drug Addiction: An Introduction.
3: Mice and Alcohol.
4: Alcohol and Rats.
5: Nonhuman Primate Models of Alcohol Abuse and Alcoholism.
6: Zebrafish and Alcohol.
7: Alcohol and Drosophila melanogaster.
8: Animal Models of Addiction other than Alcohol: Amphetamines.
9: Animal Models of Addiction: Cannabinoids.
10: Animal Models of Drug Addiction: Cocaine.
11: Effects of Nicotine in Animal Models of Drug Addiction Across Species.
12: Preclinical Animal Studies: Alcohol.
13: Preclinical Animal Studies: Cannabinoids.
14: Preclinical Animal Studies: Cocaine.
15: Preclinical Animal Studies: Nicotine.
16: Preclinical Animal Studies: Opiates.
17: Overview of Animal Models of Drug Addiction: Commonalities to Human Addiction.
18: Neuroscience.
19: Common Mechanisms of Addiction.
20: Neuroadaptive Changes that Result from Chronic Drug Exposure.
21: The Dark Side of Addiction: Dysregulated Neuroadaptation of Emotional Neurocircuits.
22: Integrating Body and Brain Systems in Addiction Neuroscience.
23: Brain Sites and Neurotransmitter Systems Mediating the Reinforcing Effects of Alcohol.
24: The Mesolimbic Dopamine Reward System and Drug Addiction.
25: Molecular and Functional Changes in Receptors: GABA and Chronic Alcohol Consumption.
26: Serotonin and Behavioral Stimulant Effects of Addictive Drugs.
27: The Role of Glutamate Receptors in Addiction.
28: Molecular and Cellular Mechanisms of Addiction.
29: Common Molecular Mechanisms and Neurocircuitry in Alcohol and Nicotine Addiction.
30: The Role of Brain Development in Drug Effect and Drug Response.
31: Molecular Targets of Ethanol in the Developing Brain.
32: Addiction, Hippocampal Neurogenesis, and Neuroplasticity in the Adult Brain.
33: Neurogenesis and Addictive Disorders.
34: Neural Mechanisms of Learning: Animal Models of Cocaine Addiction.
35: Memory Reconsolidation and Drugs of Abuse.
36: Binge Drinking and Withdrawal: Neural Mechanisms in Humans.
37: The Neural Basis of Decision Making in Addiction.
38: Addiction and the Human Adolescent Brain.
39: Neuropsychological Precursors and Consequences of Addiction.
40: Human Neurophysiology: EEG and Quantitative EEG in Addiction Research.
41: Incentive Salience and the Transition to Addiction.
42: The Neurobiological Basis of Personality Risk for Addiction.
43: Neuroeconomics and Addiction: Integrating Neuroscience, Cognition, and Behavioral Economics.
44: Common Neural Mechanisms in Obesity and Drug Addiction.
45: Brain Mechanisms of Addiction Treatment Effects.
46: Genetics of Ecstasy (MDMA) Use.
47: Genetics of Nicotine Addiction.
48: Genetics.
49: Intermediate Phenotypes/Endophenotypes and Pathways to Addiction.
50: Twin Studies and the Heritability of Substance Use Disorders.
51: The Epigenetic Consequences of Drinking.
52: Genetics of Alcohol Use Disorders.
53: Genetics of Opioid Addiction.
54: The Genetics of Cannabis Use and Cannabis Use Disorders.
55: The Genetics of Drugs of Abuse Metabolism.
56: Addiction Neuroethics: Ethical and Social Implications of Genetic and Neuroscience Research on Addiction.
57: Neuropharmacology/Imaging/Genetics.
58: Multinuclear Magnetic Resonance Methods and the Study of Mechanisms of Addiction in Humans.
59: Neuropharmacology of Nicotine.
60: Neuropharmacology of Cocaine and Amphetamine.
61: Neurobiology of Methamphetamine.
62: Neuropharmacology of Cannabinoids.
63: Neuropharmacology of Benzodiazepines.
64: Neuropharmacology of Ecstasy (MDMA) and Other Designer Drugs.
65: Neuropharmacology of Lysergic Acid Diethylamide (LSD) and Other Hallucinogens.
66: Neuropharmacology of Inhalants.
67: Alcohol Neuroimaging in Humans.
68: Neuroimaging of Nicotine and Tobacco Smoking in Humans.
69: Ecstasy (MDMA) and other designer drugs Neuroimaging.
70: Opioids Neuroimaging.
71: Neuroimaging in Problem Gambling.
72: Cocaine and Amphetamine Neuroimaging in Small Rodents.
73: The Impact of Regular Cannabis Use on the Human Brain: A Review of Structural Neuroimaging Studies.