Essentials of Stem Cell Biology, 3rd Edition

  • Published By:
  • ISBN-10: 0124104274
  • ISBN-13: 9780124104273
  • DDC: 616.02774
  • Grade Level Range: College Freshman - College Senior
  • 712 Pages | eBook
  • Original Copyright 2013 | Published/Released June 2014
  • This publication's content originally published in print form: 2013

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First developed as an accessible abridgement of the successful Handbook of Stem Cells, Essentials of Stem Cell Biology serves the needs of the evolving population of scientists, researchers, practitioners, and students embracing the latest advances in stem cells. Representing the combined effort of 7 editors and more than 200 scholars and scientists whose pioneering work has defined our understanding of stem cells, this book combines the prerequisites for a general understanding of adult and embryonic stem cells with a presentation by the world's experts of the latest research information about specific organ systems. From basic biology/mechanisms, early development, ectoderm, mesoderm, endoderm, and methods to theĀ application of stem cells to specific human diseases, regulation and ethics, and patient perspectives, no topic in the field of stem cells is left uncovered.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
List of Contributors.
1: Introduction to Stem Cells.
2: Why Stem Cell Research? Advances in the Field.
3: ‘Stemness’: Definitions, Criteria, and Standards.
4: Pluripotent Stem Cells from Vertebrate Embryos: Present Perspective and Future Challenges.
5: Embryonic Stem Cells in Perspective.
6: The Development of Epithelial Stem Cell Concepts.
7: Basic Biology and Mechanisms.
8: Stem Cell Niches.
9: Mechanisms of Stem Cell Self-Renewal.
10: Cell Cycle Regulators in Stem Cells.
11: How Cells Change Their Phenotype.
12: Tissue and Organ Development.
13: Differentiation in Early Development.
14: Stem Cells Derived from Amniotic Fluid.
15: Stem and Progenitor Cells Isolated from Cord Blood.
16: The Nervous System.
17: Sensory Epithelium of the Eye and Ear.
18: Epithelial Skin Stem Cells.
19: Hematopoietic Stem Cells.
20: Peripheral Blood Stem Cells.
21: Multipotent Adult Progenitor Cells.
22: Mesenchymal Stem Cells.
23: Skeletal Muscle Stem Cells.
24: Stem Cells and the Regenerating Heart.
25: Cell Lineages and Stem Cells in the Embryonic Kidney.
26: Adult Liver Stem Cells.
27: Pancreatic Stem Cells.
28: Stem Cells in the Gastrointestinal Tract.
29: Methods.
30: Induced Pluripotent Stem Cells.
31: Embryonic Stem Cells: Derivation and Properties.
32: Isolation and Maintenance of Murine Embryonic Stem Cells.
33: Approaches for Derivation and Maintenance of Human Embryonic Stem Cells: Detailed Procedures and Alternatives.
34: Derivation and Differentiation of Human Embryonic Germ Cells.
35: Genomic Reprogramming.
36: Applications.
37: Neural Stem Cells – Therapeutic Applications in Neurodegenerative Diseases.
38: Adult Progenitor Cells as a Potential Treatment for Diabetes.
39: Burns and Skin Ulcers.
40: Stem Cells and Heart Disease.
41: Stem Cells for the Treatment of Muscular Dystrophy.
42: Cell Therapy for Liver Disease: From Hepatocytes to Stem Cells.
43: Orthopedic Applications of Stem Cells.
44: Embryonic Stem Cells in Tissue Engineering.
45: Regulation and Ethics.
46: Ethical Considerations.
47: Overview of the FDA Regulatory Process.
48: It’s Not about Curiosity, It’s about Cures.