Drug Discovery and Evaluation: Pharmacological Essays, 3rd Edition

  • Published By:
  • ISBN-10: 3540709959
  • ISBN-13: 9783540709954
  • Grade Level Range: College Freshman - College Senior
  • 2071 Pages | eBook
  • Original Copyright 2007 | Published/Released May 2008
  • This publication's content originally published in print form: 2007

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About

Overview

  • Updated to include the latest methods in molecular biology and genetic engineering
  • Practical guide for testing and evaluating the pharmacological effects of potential new drugs
  • Includes legal regulations of animal experiments
  • Fully searchable CD-ROM included
  • More than 1,000 assays in an easy-to-use and uniform format

    This new edition has been updated to include the latest methods in molecular biology and genetic engineering. It contains a comprehensive selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic respiratory, renal and immunomodulatory activities. Each of the more than 1,000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. An accompanying, fully searchable CD-ROM allows easy identification of specific tests. An appendix with up-to-date guidelines and legal regulations for animal experiments in various countries will help the reader to plan experiments more effectively.

  • Table of Contents

    Front Cover.
    Half Title Page.
    Title Page.
    Copyright Page.
    Preface to the Third Edition.
    Preface to the Second Edition.
    Preface to the First Edition.
    Contents.
    Contributors.
    1: Strategies in Drug Discovery and Evaluation.
    2: Cardiovascular Activity Part 1.
    3: Cardiovascular Activity Part 2.
    4: Cardiovascular Activity Part 3.
    5: Cardiovascular Activity Part 4.
    6: Pharmacological Assays in Thrombosis and Haemostasis.
    7: Activity on Urinary Tract.
    8: Respiratory Activity.
    9: Psychotropic and Neurotropic Activity.
    10: Drug Effects on Learning and Memory.
    11: Effects on Peripheral Nerve Function.
    12: Analgesic, Anti-inflammatory, and Anti-pyretic Activity.
    13: Antiarthrotic and Immunomodulatory Activity.
    14: Activity on the Gastrointestinal Tract.
    15: Antidiabetic Activity.
    16: Anti-obesity Activity.
    17: Anti-Atherosclerotic Activity.
    18: Endocrinology.
    19: Ophthalmologic Activity.
    20: Pharmacological Models in Dermatology.
    21: Guidelines for the Care and Use of Laboratory Animals.
    Index.
    Front Cover.
    Half Title Page.
    Title Page.
    Copyright Page.
    Preface to the Third Edition.
    Preface to the Second Edition.
    Preface to the First Edition.
    Contents.
    Contributors.
    1: Strategies in Drug Discovery and Evaluation.
    2: Cardiovascular Activity Part 1.
    3: Cardiovascular Activity Part 2.
    4: Cardiovascular Activity Part 3.
    5: Cardiovascular Activity Part 4.
    6: Pharmacological Assays in Thrombosis and Haemostasis.
    7: Activity on Urinary Tract.
    8: Respiratory Activity.
    9: Psychotropic and Neurotropic Activity.
    10: Drug Effects on Learning and Memory.
    11: Effects on Peripheral Nerve Function.
    12: Analgesic, Anti-inflammatory, and Anti-pyretic Activity.
    13: Antiarthrotic and Immunomodulatory Activity.
    14: Activity on the Gastrointestinal Tract.
    15: Antidiabetic Activity.
    16: Anti-obesity Activity.
    17: Anti-Atherosclerotic Activity.
    18: Endocrinology.
    19: Ophthalmologic Activity.
    20: Pharmacological Models in Dermatology.
    21: Guidelines for the Care and Use of Laboratory Animals.
    Index.