Magnetic Resonance Spectroscopy, 1st Edition

  • Published By:
  • ISBN-10: 0124016979
  • ISBN-13: 9780124016972
  • DDC: 616.804754
  • Grade Level Range: College Freshman - College Senior
  • 398 Pages | eBook
  • Original Copyright 2013 | Published/Released June 2014
  • This publication's content originally published in print form: 2013

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Magnetic Resonance Spectroscopy covers how MRS is acquired, what it can measure, application to common research and clinical questions, and the advantages and limitations of the technique. Chapters are authored by experts in each topic area, and the book is written with a non-expert audience in mind. Magnetic resonance spectroscopy (MRS) is a noninvasive imaging technique that allows quantification of many neurochemicals. MRS is used in clinical neuroscience as a method for investigating brain neurochemistry, critical to understanding neurological and psychiatric disease. Improved acquisition and analysis approaches have increased interest in its use for traditional clinical applications and neuroscience research; this book meets the growing need of neuroscientists, neurologists, psychiatrists, and radiologists for reliable information on the technique.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
1: Technical Aspects—How MRS is Acquired.
2: Basis of Magnetic Resonance.
3: Localized Single-Voxel Magnetic Resonance Spectroscopy, Water Suppression, and Novel Approaches for Ultrashort Echo-Time Measurements.
4: Technical Considerations for Multivoxel Approaches and Magnetic Resonance Spectroscopic Imaging.
5: Spectral Editing and 2D NMR.
6: Spectral Quantification and Pitfalls in Interpreting Magnetic Resonance Spectroscopic Data: What To Look Out For.
7: Biochemistry — What Underlies the Signal?.
8: N-Acetylaspartate and N-Acetylaspartylglutamate in Central Nervous System Health and Disease.
9: The Biochemistry of Creatine.
10: The Biochemistry of Choline.
11: Glutamate.
12: Other Significant Metabolites: Myo-Inositol, GABA, Glutamine, and Lactate.
13: Applications of Proton-MRS.
14: Usefulness of Proton Magnetic Resonance Spectroscopy in the Clinical Management of Brain Tumors.
15: Multiple Sclerosis and Inflammatory Diseases.
16: Epilepsy.
17: Stroke and Cerebral Ischemia.
18: Use of MRS in Inborn Errors of Metabolism: Canavan’s Disease and MRS in Differential Diagnosis.
19: MRS of Psychiatric Disorders.
20: Preclinical and Clinical Applications of 1H MRS in the Spinal Cord.
21: Interindividual Differences in Behavior and Plasticity.
22: MRS in Development and Across the Life Span.
23: Hormonal Influences on Magnetic Resonance Spectroscopy Measures.
24: Magnetic Resonance Spectroscopy in Neuroenergetics and Neurotransmission.
25: Applications of Non-Proton MRS.
26: Quantitative Metabolic Magnetic Resonance Imaging of Sodium, Oxygen, Phosphorus and Potassium in the Human Brain: A Rationale for Bioscales in Clinical Applications.
27: Carbon (13C) MRS.
28: Hyperpolarized Magnetic Resonance Imaging and Spectroscopy of the Brain.