Store-Operated Calcium Channels, 1st Edition

  • Published By:
  • ISBN-10: 0124079385
  • ISBN-13: 9780124079380
  • DDC: 572.516
  • Grade Level Range: College Freshman - College Senior
  • 298 Pages | eBook
  • Original Copyright 2013 | Published/Released June 2014
  • This publication's content originally published in print form: 2013

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Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels. Contributors are authoritative researchers who have produced important advances in the field. The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject.

Table of Contents

Front Cover.
Half Title Page.
Editorial Board.
Title Page.
Copyright Page.
Previous Volumes in Series.
1: Store-Operated Orai Channels: Structure and Function.
2: Stim–orai Interactions That Control the Crac Channel.
3: Structure and Function of Endoplasmic Reticulum Stim Calcium Sensors.
4: On the Stoichiometry of Resting and Activated Crac Channels.
5: Alternative Forms of the Store-Operated Calcium Entry Mediators, Stim1 and Orai1.
6: The Arc Channel—An Endogenous Store-Independent Orai Channel.
7: Contribution and Regulation of TRPC Channels in Store-Operated Ca2 + Entry.
8: Molecular Regulation of the Pore Component of CRAC Channels, Orai1.
9: Emerging Roles for Native Orai Ca2+ Channels in Cardiovascular Disease.
10: The Neglected Crac Proteins Orai2, Orai3, and Stim2.
Other Back Matter.