Comprehensive Biotechnology, 2nd Edition

  • Michael Butler
  • Published By:
  • ISBN-10: 0080885047
  • ISBN-13: 9780080885049
  • DDC: 660.6
  • Grade Level Range: College Freshman - College Senior
  • 4959 Pages | eBook
  • Original Copyright 2011 | Published/Released September 2012
  • This publication's content originally published in print form: 2011

  • Price:  Sign in for price

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
General Preface.
Volume Editors.
Section Editors.
Contributors for All Volumes.
1: Introduction.
2: Amino Acid Metabolism.
3: Enzyme Biocatalysis.
4: Immobilized Biocatalysts.
5: Lipids, Fatty Acids.
6: DNA Cloning in Plasmid Vectors.
7: Structure and Biosynthesis of Glycoprotein Carbohydrates.
8: Nucleotide Metabolism.
9: Organic Acids.
10: Peptides and Glycopeptides.
11: Protein Structural Analysis.
12: Secondary Metabolites.
13: Cell Line Isolation and Design.
14: Cell Preservation Technology.
15: Cytoskeleton and Cell Motility.
16: Design of Culture Media.
17: Protein Folding in the Endoplasmic Reticulum.
18: Extremophiles.
19: Metabolic Design and Control for Production in Prokaryotes.
20: Microbial Growth Dynamics.
21: Modes of Culture/Animal Cells.
22: Modes of Culture/Microbial.
23: Photosynthesis and Photoautotrophy.
24: Protein Expression in Insect Cells.
25: Stem Cells.
26: Structural Organization of Cells – The Cytoskeleton.
27: Viruses Produced from Cells.
28: Cell Transfection.
29: mRNA Translation and Recombinant Gene Expression from Mammalian Cell Expression Systems.
30: Posttranslation Modifications Other than Glycosylation.
31: Engineering Protein Folding and Secretion in Eukaryotic Cell Factories.
32: Glycomics.
33: Metabolomics – The Combination of Analytical Biochemistry, Biology, and Informatics.
34: Theory and Applications of Proteomics.
35: Systems Metabolic Engineering for the Production of Non-Innate Chemical Compounds.
36: Apoptosis: The Signaling Pathways and Their Control.
37: Design Principles of Self-Assembling Peptides and their Potential Applications.
38: Rational Design of Strategies Based on Metabolic Control Analysis.
39: Unfolded Protein Response.
40: Cell Migration.
41: Biofilms.
42: Flow Cytometry.
43: Biological Imaging by Superresolution Light Microscopy.
44: Cell Isolation from Tissue.
45: Nanobiotechnology.
46: Effects of Shear Stress on Cells.
47: Viruses and Virus-Like Particles in Biotechnology: Fundamentals and Applications.
48: Mathematical Models in Biotechnology.
49: Immunoassays in Biotechnology.
50: Mass Spectrometry.
51: Bioprocessing Techniques.
Half Title Page.
Title Page.
Copyright Page.
1: Bioengineering at the Interface Between Science and Society.
2: Cellular Systems.
3: Cell Growth Dynamics.
4: Reaction Kinetics and Stoichiometry.
5: Bioreactor Fluid Dynamics.
6: Mixing in Bioreactor Vessels.
7: Genetic Engineering.
8: Bio-Feedstocks.
9: Substrate Hydrolysis: Methods, Mechanism, and Industrial Applications of Substrate Hydrolysis.
10: Medium Formulation and Development.
11: Sterilization in Biotechnology.
12: Inoculum Preparation.
13: Bioreactor Engineering.
14: Stirred Tank Bioreactors.
15: Airlift Bioreactors.
16: Shake-Flask Bioreactors.
17: Photobioreactors.
18: Disposable Bioreactors.
19: Membrane Bioreactors.
20: Microbioreactors.
21: Biofilters.
22: Enzyme Bioreactors.
23: Immobilized Cell Bioreactors.
24: Bioreactors for Solid-State Fermentation.
25: Bioreactors for Plant Cell Culture.
26: Bioreactors for Animal Cell Cultures.
27: Bioreactors for Tissue Engineering: Design, Applications, and Monitoring.
28: Recombinant Technology.
29: Metabolic Regulation Analysis and Metabolic Engineering.
30: Proteomics, Protein Engineering.
31: Heterologous Protein Expression.
32: Biotransformations.
33: Immobilized Enzymes.
34: Immobilization Technology: Cells.
35: Immobilized Viable Cell Biocatalysts: A Paradoxical Development.
36: Fermentation Processes: Quantitative Aspects.
37: Fed-Batch Fermentation – Design Strategies.
38: Continuous Operation.
39: Multistage Continuous High Cell Density Culture.
40: Integrated Production and Separation.
41: Product Recovery.
42: Membrane Systems and Technology.
43: Cell Disruption.
44: Autolysis of Yeasts.
45: Precipitation and Crystallization.
46: Adsorption and Chromatography.
47: Modeling Chromatographic Separation.
48: Aqueous Two-Phase Systems.
49: Foam Separations.
50: Drying.
51: Chiral Separations.
52: Lab on a Chip – Future Technology for Characterizing Biotechnology Products.
53: Protein Refolding/Renaturation.
54: Biogas Production.
55: Purification Process Design and the Influence of Product and Technology Platforms.
56: The Proportion of Downstream Costs in Fermentative Production Processes.
57: Biorefinery Engineering.
58: Instrumentation and Analytical Methods.
59: Life Cycle Assessment in Biotechnology.
60: Metabolic Control.
61: Fuzzy Control of Bioprocess.
62: Online Control Strategies.
63: Process Optimization.
64: Micro-Biochemical Engineering.
65: Sustainability.
66: Nanostructured Biocatalysts.
67: Aseptic Operations.
68: Oxygen Mass Transfer in Bioreactors.
69: Cavitation in Biotechnology.
70: Flow Cytometry: A High-Throughput Technique for Microbial Bioprocess Characterization.
71: Cleaning in Place.
72: Ionic Liquids.
73: Supercritical Fluids.
74: Computational Fluid Dynamics.
Half Title Page.
Title Page.
Copyright Page.
1: Industrial Enzymes.
2: Multifunctional Enzyme Systems for Plant Cell Wall Degradation.
3: Ethanol Production from Sugar-Based Feedstocks.
4: Ethanol from Starch-Based Feedstocks.
5: Biofuels from Cellulosic Feedstocks.
6: Biodiesel.
7: Biofuels and Bioenergy: Acetone and Butanol.
8: Microbial Production of 2,3-Butanediol.
9: Biogas.
10: Biohydrogen.
11: Biofuel from Microalgae.
12: Citric Acid.
13: Gluconic and Itaconic Acids.
14: Organic Acids: Succinic and Malic Acids.
15: Fumaric Acid.
16: Industrial Production of Lactic Acid.
17: Acetic and Propionic Acids.
18: Acrylic Acid.
19: Butyric Acid.
20: PHA/PHB.
21: 1,3-Propanediol and Polytrimethyleneterephthalate.
22: Antibiotics: The Miracle Menaced.
23: Penicillins and Cephalosporins.
24: Tetracyclines and Tetracycline Derivatives.
25: Microbial Secondary Metabolites.
26: Plant Secondary Metabolites.
27: Biocatalyzed Production of Fine Chemicals.
28: Production of Recombinant Proteins by Microbes and Higher Organisms.
29: Vaccines.
30: Manufacturing Recombinant Proteins in Kg-Ton Quantities Using Animal Cells in Bioreactors.
31: Recent and Emerging Trends and Concerns Related to the Manufacturing and Testing of Monoclonal Antibodies Intended for Clinical Use.
32: Therapeutic Enzymes and Biomimetic Substrates.
33: Cell-Free Production of Pharmaceutical Proteins.
34: Combination Products are Not Solely Biological Products, Drugs, or Devices: A Regulatory Perspective.
35: Cellular Therapies.
36: Gene Therapies.
37: Regulatory Aspects of Chemistry Manufacturing and Controls for Investigational New Drug Applications and Biologic License Applications to the United States Food and Drug Administration.
38: Raw Materials in the Manufacture of Biotechnology Products.
39: Characterization of Biotechnological/Biological/Biosimilar Products.
40: Protein Glycosylation.
41: Immunogenicity Assay Development and Validation.
42: Process Analytical Technology in Bioprocess Development and Manufacturing.
43: Process Validation.
44: Follow-On Protein Products: Scientific Issues, Developments, and Challenges.
45: Amino Acid Production.
46: Lysine: Industrial Uses and Production.
47: Food-Grade Enzymes.
48: Proteases.
49: Application of Enzymes and Microbes for the Industrial Production of Vitamins and Vitamin-Like Compounds.
50: Fungal Biotechnology in Food and Feed Processing.
51: Metabolic Engineering.
52: Synthetic Biology: An Overview.
53: Industrial Biotechnology and Commodity Products.
54: Bioreactors for Commodity Products.
55: Integrating Process Scouting Devices (PSDs) with Bench-Scale Devices.
56: Overview of Downstream Processing in the Biomanufacturing Industry.
57: Nanotechnology.
58: Biosurfactants.
59: Bioleaching and Biomining for the Industrial Recovery of Metals.
60: Biological Control.
Half Title Page.
Title Page.
Copyright Page.
1: Introduction.
2: Plant Biotechnology and GMOs.
3: Bioactivity of Herbicides.
4: Starch Biosynthesis in Higher Plants: The Starch Granule.
5: Starch Biosynthesis in Higher Plants: The Enzymes of Starch Synthesis.
6: Metabolic Engineering of Higher Plants to Produce Bio-Industrial Oils.
7: Biodiesel – An Integrated Approach for a Highly Efficient Biofuel.
8: Matching Crops for Selected Bioproducts.
9: Nanotechnologies for Agricultural Bioproducts.
10: Transgenic Crops with Producer-Oriented Traits: Development, Application, and Impact.
11: Plant Genetic Techniques: Plant Breeder’s Toolbox.
12: Plant Bioinformatics and Microarray Technologies.
13: Increasing Photosynthesis/RuBisCO and CO2-Concentrating Mechanisms.
14: Photosynthesis and Productivity of Vascular Plants in Controlled and Field Environments.
15: Roles of Dark Respiration in Plant Growth and Productivity.
16: Improving Plant Nitrogen-Use Efficiency.
17: Circadian Clocks/Photoperiodism and Crop Quality.
18: Breadfruit: An Old Crop with a New Future.
19: Wines.
20: Sulfur Metabolism in Plants and Related Biotechnologies.
21: Emerging Roles for Plant Terpenoids.
22: Antibody Production in Planta.
23: Microalgae as Bioreactors for Production of Pharmaceutical Proteins.
24: Algal Chemostats.
25: Improvement of Ginseng by In Vitro Culture: Challenges and Opportunities.
26: Can Plants Really Improve Indoor Air Quality?.
27: Regulating the Ripening Process.
28: Pre- and Postharvest Treatments Affecting Nutritional Quality.
29: Embryo Genomics State of the Art.
30: Aquaculture Genomics: A Case Study with Catfish.
31: Epigenetics and Animal Health.
32: Quest for Novel Muscle Pathway Biomarkers by Proteomics in Beef Production.
33: From Stem Cell to Gamete.
34: Stem Cells and Animal Therapies.
35: Flow Cytometric Sorting of Mammalian Sperm for Predetermination of Sex.
36: Animal Cloning: State of the Art and Applications.
37: Transgenesis.
38: Arrest or Survive: A Decision of the Early Preimplantation Embryo that Influences Fertility.
39: Heat Stress and Climate Change.
40: Analytical Methods – Functional Foods and Dietary Supplements.
41: Plant Derived Bioactives.
42: Functional Properties of Dietary Fiber.
43: Resistant Starches in Foods.
44: Plant Sterols: Nutritional Aspects.
45: Soy Protein Functionality: Emulsion and Gels.
46: Egg Components for Heart Health.
47: Enzyme Technology – Dairy Industry Applications.
48: Gut Microbiology – A Relatively Unexplored Domain.
49: Probiotics.
50: Novel Lipid Substitutes.
51: Microwave Dehydration of Food and Food Ingredients.
52: Active and Intelligent Packaging Materials.
53: Antimicrobials from Plants–Food Preservation and Shelf-Life Extension.
54: Biosensors for Foodborne Pathogen Detection.
55: Microemulsions as Nanoscale Delivery Systems.
56: Origins and Compositional Analysis of Novel Foods.
57: Nutrigenomics: A Possible Road to Personalized Nutrition.
58: Plant and Endophyte Relationships: Nutrient Management.
59: Disease Resistance/Pathology/Fusarium.
60: Plant Biochemistry: Antifungal Proteins Protecting Plants from Fungal Pathogens.
61: Biological Control and Biotechnological Amelioration in Managed Ecosystems.
62: Genetic Basis of Disease Resistance in the Honey Bee (Apis mellifera L.).
63: Food Safety, Genetically Engineered Foods and Perception.
64: Socio-Environmental Factors Influencing Food Behavior.
65: Policy and Novel Foods from Animal Sources.
Half Title Page.
Title Page.
Copyright Page.
1: Functional Biomaterials.
2: Biomaterials/Cryogels.
3: Biomaterials: Electrospinning.
4: Mesoscale Engineering of Collagen as a Functional Biomaterial.
5: Biomaterials: Temperature-Responsive Polymer.
6: Surface Modification to Improve Biocompatibility.
7: Cryopreservation: Organ Preservation.
8: The Artificial Organ: Cell Encapsulation.
9: Isolation of Mesenchymal Stem Cells from Bone Marrow Aspirate.
10: Nanoimprint Lithography and Its Application in Tissue Engineering and Biosensing.
11: Microfluidic Technology and Its Biological Applications.
12: Multifunctional Biosensor Development and Manufacture.
13: Treating Intracranial Aneurysms – A Review of Existing and Emerging Methods.
14: RNA Interference (RNAi) Technology.
15: Rheology and Its Applications in Biotechnology.
16: Biological Fluid Mechanics: Integrative and Multiscale Computational Modeling.
17: Mechanobiology of Bone.
18: Biofluids
Half Title Page.
Title Page.
Copyright Page.
1: Biodegradation: Principles, Scope, and Technologies.
2: Systems Biology Approaches to Bioremediation.
3: Molecular Approaches for the Analysis of Natural Attenuation and Bioremediation.
4: New Developments and Applications of Microarrays for Microbial Community Analysis in Natural and Impacted Ecosystems.
5: Metagenomics for Bioremediation.
6: In Situ Bioremediation.
7: Bioaugmentation as a Strategy for the Treatment of Persistent Pollutants.
8: Bioavailability and Bioaccessibility as Key Factors in Bioremediation.
9: Biodegradability of Recalcitrant Aromatic Compounds.
10: Proteomic Applications to Elucidate Bacterial Aromatic Hydrocarbon Metabolic Pathways.
11: Rieske-Type Dioxygenases: Key Enzymes in the Degradation of Aromatic Hydrocarbons.
12: Dehalogenation of Polychlorinated Dibenzo-p-Dioxins and Dibenzofurans, Polychlorinated Biphenyls, and Brominated Flame Retardants, and Potential as a Bioremediation Strategy.
13: Microbial Degradation of Polychlorinated Biphenyls.
14: Biodegradation and Bioremediation of TNT and Other Nitro Explosives.
15: Oxidative Fungal Enzymes for Bioremediation.
16: Biotechnological Strategies Applied to the Decontamination of Soils Polluted with Heavy Metals.
17: Phytofiltration of Heavy Metals: Assessment of the Key Factors Involved in the Design of a Sustainable Process.
18: Phycoremediation: Current Challenges and Applications.
19: Transgenic Plants and Associated Bacteria for Phytoremediation of Organic Pollutants.
20: Potential for Enhanced Phytoremediation of Landfills Using Biosolids – A Review.
21: Methanotrophs: Multifunctional Bacteria with Promising Applications in Environmental Bioengineering.
22: Petroleum Spill Control with Biological Means.
23: Biological Wastewater Treatment Systems.
24: Ecological Models: Wastewater Treatment Models.
25: Activated Sludge Model-Based Modeling of Membrane Bioreactor Processes.
26: Biological Nitrogen Removal from Domestic Wastewater.
27: Biotechnological Methods for Nutrient Removal from Wastewater with Emphasis on the Denitrifying Phosphorus Removal Process.
28: Constructed Wetlands for Water Treatment.
29: Attached Growth Biological Systems in the Treatment of Potable Water and Wastewater.
30: Kinetics and Modeling of Anaerobic Treatment and Biotransformation Processes.
31: Anaerobic Treatment of Organic Sulfate-Rich Wastewaters.
32: Biotechnological Aspects of the Use of Methane as Electron Donor for Sulfate Reduction.
33: Sulfate Reduction for Inorganic Waste and Process Water Treatment.
34: Anaerobic Biotreatment of Municipal Sewage Sludge.
35: Anaerobic Digestion of the Organic Fraction of Municipal Solid Waste for Methane Production.
36: Occurrence, Toxicity, and Biodegradation of Selected Emerging Priority Pollutants in Municipal Sewage Sludge.
37: Biodegradation of Micropollutants and Prospects for Water and Wastewater Biotreatment.
38: Microbial Sensors for Monitoring and Control of Aerobic, Anoxic, and Anaerobic Bioreactors in Wastewater Treatment.
39: Efficiency and Sustainability of Urban Wastewater Treatment with Maximum Separation of the Solid and Liquid Fraction.
40: Biotreatment of Drinking Water.
41: Agriculture and Agro-Industrial Wastes, Byproducts, and Wastewaters.
42: Production of Fine Chemicals by (Bio)Transformation of Agro-Food Byproducts and Wastes.
43: Management and Processing of Food Wastes.
44: Application of White-Rot Fungi in Transformation, Detoxification, or Revalorization of Agriculture Wastes.
45: A Microbial Perspective on Ethanolic Lignocellulose Fermentation.
46: Techno-Economic Aspects of Ethanol Production from Lignocellulosic Agricultural Crops and Residues.
47: Biohydrogen Production from Agricultural Agrofood-Based Resources.
48: Microbial Fuel Cells and Bioelectrochemical Systems.
49: Vanillin Production from Agro-Industrial Wastes.
50: Mixed Culture Processes for Polyhydroxyalkanoate Production from Agro-Industrial Surplus/Wastes as Feedstocks.
51: Biosorption for Industrial Applications.
52: BT Technology for the Control of Methane Emissions from Permafrost and Natural Gas Hydrates.
53: Molecular Aspects of Microbial Dissimilatory Reduction of Radionuclides: A Review.
54: Today’s Wastes, Tomorrow’s Materials for Environmental Protection.
Nomenclature Guidelines.
Permission Acknowledgements.