Half Title Page.
1: Methods in Enzymology.
2: Computational Design of Novel Protein Binders and Experimental Affinity Maturation.
3: Mining Tertiary Structural Motifs for Assessment of Designability.
4: Computational Methods for Controlling Binding Specificity.
5: Flexible Backbone Sampling Methods to Model and Design Protein Alternative Conformations.
6: OSPREY: Protein Design with Ensembles, Flexibility, and Provable Algorithms.
7: Scientific Benchmarks for Guiding Macromolecular Energy Function Improvement.
8: Molecular Dynamics Simulations for the Ranking, Evaluation, and Refinement of Computationally Designed Proteins.
9: Multistate Protein Design Using Clever and Classy.
10: Using Analyses of Amino Acid Coevolution to Understand Protein Structure and Function.
11: Evolution-Based Design of Proteins.
12: Protein Engineering and Stabilization from Sequence Statistics Variation and Covariation Analysis.
13: Enzyme Engineering by Targeted Libraries.
14: Generation of High-Performance Binding Proteins for Peptide Motifs by Affinity Clamping.
15: Engineering Fibronectin-Based Binding Proteins by Yeast Surface Display.
16: Engineering and Analysis of Peptide-Recognition Domain Specificities by Phage Display and Deep Sequencing.
17: Efficient Sampling of SCHEMA Chimera Families to Identify Useful Sequence Elements.
18: Protein Switch Engineering by Domain Insertion.
19: Design of Chimeric Proteins by Combination of Subdomain-Sized Fragments.
20: α-Helix Mimicry with α/β-Peptides.