Transfusion Medicine and Hemostasis, 2nd Edition

  • Published By:
  • ISBN-10: 0123977886
  • ISBN-13: 9780123977885
  • DDC: 615.39
  • Grade Level Range: College Freshman - College Senior
  • 1014 Pages | eBook
  • Original Copyright 2013 | Published/Released May 2014
  • This publication's content originally published in print form: 2013

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The second edition of Transfusion Medicine and Hemostasis continues to be the only "pocket-size" quick reference for pathology residents and transfusion medicine fellows. It covers all topics in blood banking, transfusion medicine, and clinical and laboratory based coagulation. Short, focused chapters, organized by multiple hierarchical headings, are supplemented with up to 10 suggested reading citations. This single reference covers essentially all the topics required to meet the goals and objectives of a major program in transfusion medicine and clinical coagulation. New chapters in the coagulation testing section reflect the development of new tests available and their incorporation into clinical practice. Coverage includes essential updates on the importance of new cellular therapies, peripheral blood and bone marrow hematopoietic progenitor cells, as well as cord blood banking and regenerative medicine. The authors also examine advances in the understanding of molecular testing and pathogen reduction in two separate quality control chapters (one for blood centers and one for hospitals).

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
About the Editors.
1: Blood Banking and Transfusion Medicine.
2: Blood Banking and Transfusion Medicine – History, Industry, and Discipline.
3: Quality Principles in Transfusion Medicine.
4: Regulatory Issues in Transfusion Medicine.
5: Role of the Physician in the Blood Center.
6: Blood Donor, Donation Process and Technical Aspects of Blood Collection.
7: Apheresis Blood Component Collections.
8: Recipient-Specific Blood Donation.
9: Adverse Donor Reactions.
10: Component Preparation and Manufacturing.
11: Serologic Testing of Donor Products.
12: Overview of Infectious Disease Testing.
13: Human Immunodeficiency Virus Screening.
14: Hepatitis B Viral Screening.
15: Hepatitis C Virus Screening.
16: West Nile Virus Screening.
17: Syphilis, Human T-Cell Lymphotropic Virus, and Chagas Screening.
18: Bacterial Detection Methods.
19: Role of the Transfusion Service Physician.
20: Pretransfusion Testing.
21: Antibody Identification.
22: Direct Antiglobulin Test.
23: Molecular DNA Based Blood Group Typing.
24: ABO and H Blood Group System.
25: Rh and RhAG Blood Group Systems.
26: Kell and Kidd Blood Group Systems.
27: MNS and Duffy Blood Group Systems.
28: Lewis, I, P1PK and GLOB Blood Group Systems.
29: Other Blood Group Systems, Collections, and Series.
30: Human Platelet Antigens.
31: HLA Antigens.
32: Red Blood Cell Products.
33: Plasma Products.
34: Platelet Products.
35: Cryoprecipitate and Fibrinogen Concentrates.
36: Granulocyte Products.
37: Albumin and Related Products.
38: Human Immunoglobulin Preparations.
39: Rh Immune Globulin.
40: Coagulation Factor Products.
41: Irradiation of Blood Products.
42: Leukoreduction of Blood Products.
43: CMV-Safe Blood Products.
44: Frozen Blood Products.
45: Washed Blood Products.
46: Volume Reduced Products.
47: Pathogen Reduction Technologies.
48: Neonatal and Pediatric Transfusion Medicine.
49: Perinatal Transfusion Medicine.
50: Autoimmune Hemolytic Anemias.
51: Transfusion Management in Patients with Hemoglobinopathies.
52: Transfusion of Patients Undergoing Hematopoietic Stem Cell and Solid Organ Transplantation.
53: Transfusion Management of Patients Receiving Antithrombotic Therapy.
54: Blood Transfusion in Economically Restricted and Developing Countries.
55: Management of Patients Who Refuse Blood Transfusion.
56: Platelet Transfusion Refractory Patients.
57: Massive Transfusion.
58: Patient Blood Management.
59: Overview of Adverse Events and Outcomes Following Transfusion.
60: Febrile Non-Hemolytic Transfusion Reactions.
61: Allergic Transfusion Reactions.
62: Acute Hemolytic Transfusion Reactions.
63: Delayed Hemolytic Transfusion Reactions.
64: Transfusion-Associated Circulatory Overload.
65: Transfusion-Related Acute Lung Injury.
66: Septic Transfusion Reactions.
67: Metabolic, Hypotensive and Other Acute Reactions and Complications.
68: Post-Transfusion Purpura.
69: Transfusion-Associated Graft-Versus-Host Disease.
70: Transfusion-Related Immunomodulation.
71: Iron Overload.
72: Transfusion-Transmitted Diseases.
73: Overview of Therapeutic Apheresis.
74: Therapeutic Plasma Exchange.
75: Therapeutic Erythrocytapheresis.
76: Therapeutic Thrombocytapheresis.
77: Therapeutic Leukocytapheresis and Adsorptive Cytapheresis.
78: Extracorporeal Photopheresis.
79: LDL Apheresis.
80: Immunoadsorption.
81: Therapeutic Phlebotomy.
82: Overview of Cellular Therapy.
83: Hematopoietic Progenitor Cell Products Derived from Bone Marrow and Peripheral Blood.
84: Cord Blood Banking.
85: Regenerative Medicine.
86: Tissue Banking in the Hospital Setting.
87: Adverse Events Associated with Hematopoietic Progenitor Cell Product Infusion.
88: Quality and Regulatory Issues in Cellular Therapy.
89: Hemostasis.
90: Overview of the Coagulation System.
91: Approach to the Bleeding Patient.
92: Congenital Thrombocytopenia.
93: Fetal and Neonatal Alloimmune Thrombocytopenia.
94: Acquired Neonatal Thrombocytopenia.
95: Bernard-Soulier Syndrome and Other GPIb-IX–V Related Receptor Defects.
96: Glanzmann Thrombasthenia.
97: Platelet Storage Granule Defects.
98: Failure to Release and Aspirin-like Defects.
99: Acute (Childhood) Immune Thrombocytopenia.
100: Chronic Immune Thrombocytopenia.
101: Drug-Induced Thrombocytopenia.
102: Heparin-Induced Thrombocytopenia.
103: Autoimmune Lymphoproliferative Syndrome.
104: Hemolytic Uremic Syndrome.
105: Thrombotic Thrombocytopenic Purpura.
106: Antiphospholipid Syndrome.
107: von Willebrand Disease.
108: Hemophilia A.
109: Hemophilia B.
110: Congenital Disorders of Fibrinogen.
111: Factor XIII, α2-Antiplasmin and Plasminogen Activator Inhibitor-1 Deficiencies.
112: Factor XI Deficiency.
113: Factor VII Deficiency.
114: Factor II, Factor V and Factor X Deficiencies.
115: Bleeding Disorders in Pregnancy.
116: Vascular Bleeding Disorders.
117: Bleeding Risks with Liver Disease.
118: Bleeding Risks with Vitamin K Deficiency.
119: Bleeding Risks with Cardiac Disease.
120: Bleeding Risks with Renal Disease.
121: Bleeding Disorders in Cancer Patients.
122: Disseminated Intravascular Coagulopathy.
123: Acquired Coagulation Factor Inhibitors.
124: Overview of Purposes of Hemostasis Testing and Common Sources of Error.
125: Thrombin Time and Fibrinogen Determination.
126: Prothrombin Time.
127: Activated Partial Thromboplastin Time.
128: Mixing Studies.
129: Coagulation Factor Testing.
130: Specific Factor Inhibitor Testing.
131: Laboratory Diagnosis of Lupus Anticoagulant and Anti-Phospholipid Antibodies.
132: Laboratory Diagnosis of Inherited von Willebrand Disease.
133: Laboratory Diagnosis of Acquired von Willebrand Syndrome.
134: Laboratory Assessment of Treatment of von Willebrand Disease.
135: Measurement of Platelet Count, Mean Platelet Volume and Reticulated Platelets.
136: Platelet Function Analyzer.
137: Platelet Aggregation Studies.
138: Laboratory Diagnosis of Platelet Function Defects.
139: Antiplatelet Therapy Monitoring.
140: Laboratory Diagnosis of Heparin-Induced Thrombocytopenia.
141: Laboratory Evaluation of Thrombotic Thrombocytopenic Purpura.
142: Fibrinolytic Testing.
143: Laboratory Evaluation of Factor XIII Deficiency.
144: Laboratory Techniques in Fibrinolysis Testing.
145: Laboratory Evaluation of Long-Term Thrombophilic Disorders.
146: Antithrombin Testing.
147: Protein C Deficiency Evaluation.
148: Protein S Deficiency Evaluation.
149: Testing for Activated Protein C Resistance.
150: Molecular Testing for Factor V Leiden and Prothrombin Gene Mutations in Inherited Thrombophilia.
151: Laboratory Management of Disseminated Intravascular Coagulation.
152: Circulating Microparticles.
153: Monitoring of Heparins, Fondaparinux, Direct Thrombin Inhibitors and Oral Anti-Xa Medications.
154: Laboratory Support for Warfarin Monitoring.
155: Thrombin Generation Assays.
156: Thromboelastography/Thromboelastometry.
General Handbook References.