Accurate Results in the Clinical Laboratory, 1st Edition

  • Published By:
  • ISBN-10: 0124158587
  • ISBN-13: 9780124158580
  • DDC: 616.075
  • Grade Level Range: College Freshman - College Senior
  • 382 Pages | eBook
  • Original Copyright 2013 | Published/Released June 2014
  • This publication's content originally published in print form: 2013

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This practical, easy-to-use guide addresses interference issues in all laboratory tests, including patient epigenetics, process of specimen collection, enzymes, biomarkers. Clinicians and laboratory scientists can therefore rely on one reference which speaks to both their needs of accurate specimen analysis and optimal patient care. Erroneous hospital and pathology laboratory results can be confusing and problematic, especially in acute care situations. While some factors creating interference, can be identified in the laboratory, detecting many others is often dependent on clinical details unavailable to the laboratory scientists or pathologists. Therefore, clinicians must become proficient in identifying such erroneous reports, and working with pathologists and laboratory scientists so that they can understand the source of such interferences, correct the results, and then decide what course of action must be followed for proper patient management.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
List of Contributors.
1: Variation, Errors, and Quality in the Clinical Laboratory.
2: Effect of Age, Gender, Diet, Exercise, and Ethnicity on Laboratory Test Results.
3: Effect of Patient Preparation, Specimen Collection, Anticoagulants, and Preservatives on Laboratory Test Results.
4: Sample Processing and Specimen Misidentification Issues.
5: Hemolysis, Lipemia, and High Bilirubin: Effect on Laboratory Tests.
6: Immunoassay Design and Mechanisms of Interferences.
7: Effect of Herbal Remedies on Clinical Laboratory Tests.
8: Challenges in Routine Clinical Chemistry Testing: Analysis of Small Molecules.
9: Challenges in Routine Clinical Chemistry Analysis: Proteins and Enzymes.
10: Sources of Inaccuracy in Biochemical Genetics Testing.
11: Challenges in Endocrinology Testing.
12: Pitfalls in Tumor Markers Testing.
13: Issues of Interferences in Therapeutic Drug Monitoring.
14: Limitations of Drugs of Abuse Testing.
15: Challenges in Confirmation Testing for Drugs of Abuse.
16: Alcohol Determination Using Automated Analyzers: Limitations and Pitfalls.
17: Pre-Analytical Issues and Interferences in Transfusion Medicine Tests.
18: Issues with Immunology and Serology Testing.
19: Sources of Errors in Hematology and Coagulation Testing.
20: Challenges in Clinical Microbiology Testing.
21: Sources of Errors in Molecular Testing.
22: Problems in Pharmacogenomics Testing.