Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics, 1st Edition

  • Published By:
  • ISBN-10: 047001153X
  • ISBN-13: 9780470011539
  • Grade Level Range: College Freshman - College Senior
  • 4096 Pages | eBook
  • Original Copyright 2005 | Published/Released April 2008
  • This publication's content originally published in print form: 2005

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About

Overview

Genomics and its related fields of proteomics and bioinformatics are among the most exciting and rapidly expanding disciplines at the start of the 21st century. With more and more whole genome sequences and large-scale datasets becoming available, the task is to analyze this information and use it to deliver greater understanding of how organisms function. This will lead to improvements in medicine, public health and agriculture.

This reference covers all three fields in depth, with a further volume focusing on important topics in genetics. It brings together the latest concepts in these vibrant areas and ensures a truly multidisciplinary approach. With articles for both students and more experienced scientists, this is a key reference source for everyone.

Table of Contents

Front Cover.
Title Page.
Copyright Page.
Half Title Page.
Volume Editors.
Genetics Section Editors.
Contents for Genetics.
Contents for Genomics.
Contents for Proteomics.
Contents for Bioinformatics.
Contributors to Genetics.
Preface.
1: Genetic Variation and Evolution.
2: Genetic Variation and Evaluation: Introductory Review.
3: Population Genomics: Patterns of Genetic Variation within Populations.
4: Genetic Variation and Evaluation: Specialist Reviews.
5: Modeling Human Genetic History.
6: Homeobox Gene Repertoires: Implications for the Evolution of Diversity.
7: Genetic Variation and Evaluation: Short Specialist Reviews.
8: Studies of Human Genetic History using the Y Chromosome.
9: Studies of Human Genetic History using MtDNA Variation.
10: The Genetic Structure of Human Pathogens.
11: Genetic Signatures of Natural Selection.
12: The Role of Gene Regulation in Evolution.
13: Modeling Protein Evolution.
14: Genetic Variation and Evaluation: Basic Techniques and Approaches.
15: Measuring Variation in Natural Populations: A Primer.
16: Cytogenetics.
17: Cytogenetics: Introductory Reviews.
18: Human Cytogenetics and Human Chromosome Abnormalities.
19: The Visualization of Chromosomes.
20: Cytogenetics: Specialist Reviews.
21: Meiosis and Meiotic Errors.
22: Acquired Chromosome Abnormalities: The Cytogenetics of Cancer.
23: Human X Chromosome Inactivation.
24: Cytogenetics: Short Specialist Reviews.
25: Nondisjunction.
26: Microdeletions.
27: Mosaicism.
28: Uniparental Disomy.
29: Cytogenetics of Infertility.
30: Preimplantation Genetic Diagnosis for Chromosome Abnormalities.
31: Cytogenetics: Basic Techniques and Approaches.
32: Fish.
33: Comparative Genomic Hybridization.
34: Cytogenetic Analysis of Lymphomas.
35: Human Sperm-Fish for Identifying Potential Paternal Risk Factors for Chromosomally Abnormal Reproductive Outcomes.
36: Epigenetics.
37: Epigenetics: Introductory Review.
38: Imprinting and Epigenetic Inheritance in Human Disease.
39: Epigenetics: Specialist Reviews.
40: The Histone Code and Epigenetic Inheritance.
41: Imprinting and Epigenetics in Mouse Models and Embryogenesis: Understanding the Requirement for Both Parental Genomes.
42: Imprinting in Prader–Willi and Angelman Syndromes.
43: Beckwith–Wiedemann Syndrome.
44: Imprinting at the GNAS Locus and Endocrine Disease.
45: Epigenetics: Short Specialist Reviews.
46: DNA Methylation in Epigenetics, Development, and Imprinting.
47: Epigenetic Reprogramming in Germ Cells and Preimplantation Embryos.
48: Epigenetics and Imprint Resetting in Cloned Animals.
49: Imprinted QTL in Farm Animals: A Fortuity or a Common Phenomenon?.
50: Variable Expressivity and Epigenetics.
51: Evolution of Genomic Imprinting in Mammals.
52: Rapidly Evolving Imprinted Loci.
53: Imprinting and Behavior.
54: Spreading of X-Chromosome Inactivation.
55: Initiation of X-Chromosome Inactivation.
56: Mechanisms of Epigenetic Loss of Chromosomes in Insects.
57: Epigenetic Inheritance and RNAi at the Centromere and Heterochromatin.
58: Epigenetics: Basic Techniques and Approaches.
59: Techniques in Genomic Imprinting Research.
60: Bioinformatics and the Identification of Imprinted Genes in Mammals.
61: UPD in Human and Mouse and Role in Identification of Imprinted Loci.
62: Gene Mapping.
63: Gene Mapping: Introductory Reviews.
64: Introduction to Gene Mapping: Linkage at a Crossroads.
65: Parametric Versus Nonparametric and Two-Point Versus Multipoint: Controversies in Gene Mapping.
66: Gene Mapping: Specialist Reviews.
67: Gene Mapping, Imprinting, and Epigenetics.
68: Gene Mapping and the Transition from STRPs to SNPs.
69: Gene Mapping: Short Specialist Reviews.
70: Choices in Gene Mapping: Populations and Family Structures.
71: Algorithmic Improvements in Gene Mapping.
72: Information Content in Gene Mapping.
73: Sex-Specific Maps and Consequences for Linkage Mapping.
74: Polymorphic Inversions, Deletions, and Duplications in Gene Mapping.
75: Gene Mapping: Basic Techniques and Approaches.
76: Computation of LOD Scores.