Optical Spectroscopy and Computational Methods in Biology and Medicine, 1st Edition

  • Published By:
  • ISBN-10: 9400778325
  • ISBN-13: 9789400778320
  • DDC: 541.2
  • Grade Level Range: College Freshman - College Senior
  • 540 Pages | eBook
  • Original Copyright 2014 | Published/Released June 2014
  • This publication's content originally published in print form: 2014

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This multi-author contributed volume gives a comprehensive overview of recent progress in various vibrational spectroscopic techniques and chemometric methods and their applications in chemistry, biology and medicine. In order to meet the needs of readers, the book focuses on recent advances in technical development and potential exploitations of the theory, as well as the new applications of vibrational methods to problems of recent general interest that were difficult or even impossible to achieve in the not so distant past. Integrating vibrational spectroscopy and computational approaches serves as a handbook for people performing vibrational spectroscopy followed by chemometric analysis hence both experimental methods as well as procedures of recommended analysis are described. This volume is written for individuals who develop new methodologies and extend these applications to new realms of chemical and medicinal interest.

Table of Contents

Front Cover.
Half Title Page.
Other Frontmatter.
Title Page.
Copyright Page.
List of Contributors.
1: Introduction.
2: General Overview on Vibrational Spectroscopy Applied in Biology and Medicine.
3: Integrating Optical Spectroscopy and Chemometric Methods.
4: New Techniques and Special Applications.
5: Surface-Enhanced Raman Scattering (SERS) in Bioscience: A Review of Application.
6: Raman Optical Activity of Biological Samples.
7: α-Amino Acids in Water: A Review of VCD and Roa Spectra.
8: Electronic Circular Dichroism Spectroscopy in Structural Analysis of Biomolecular Systems.
9: Biologically Relevant Molecules Studied in Low Temperature Inert Matrices.
10: Two-Dimensional?Mid-Infrared?Correlation? Spectroscopy in Protein Research.
11: Biological Applications.
12: Qualitative and Quantitative FT-Raman Analysis of Plants.
13: Chemometric Analysis of Raman and IR Spectra of Natural Dyes.
14: Structural and Spatial Analysis of Carotenoids in a Single Cell Monitored by Raman Spectroscopy.
15: Biomedical Applications.
16: Raman Spectra of Solid Amino Acids: Spectral Correlation Analysis as the First Step Towards Identification by Raman Spectroscopy.
17: Vibrational Spectroscopy: Disease Diagnostics and Beyond.
18: Quantitative Analysis of Disease Biomarkers Using Surface-Enhanced Raman Scattering Spectroscopy.
19: FTIR Imaging of Tissues: Techniques and Methods of Analysis.
20: Fourier Transform Infrared (Ft-Ir) Spectroscopic Imaging for Solid Tumor Histopathology.
21: Vibrational Microspectroscopy for Analysis of Atherosclerotic Arteries.