Heart Failure in the Child and Young Adult: From Bench to Bedside, 1st Edition

  • John Jefferies
  • Anthony Chang
  • Joseph Rossano
  • Robert Shaddy
  • Jeffrey Towbin Baylor College of Medicine, Houston, Texas, USA
  • Published By:
  • ISBN-10: 0128026138
  • ISBN-13: 9780128026137
  • DDC: 618.92129
  • Grade Level Range: College Freshman - College Senior
  • 824 Pages | eBook
  • Original Copyright 2018 | Published/Released June 2018
  • This publication's content originally published in print form: 2018

  • Price:  Sign in for price



This volume combines multiple etiologies for pediatric heart failure, including congenital heart disease, cardiomyopathies, infectious diseases and metabolic abnormalities. Coverage begins with the basic science of heart failure, then progresses through diagnosis, management, treatment and surgery, finally concluding with advanced special topics, including genetics, self-management and nanomedicine.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
Jefferies—Heart Failure Dedications.
List of Contributors.
Basic Science of Heart Failure.
1: Molecular and Cellular Mechanisms in Heart Failure.
2: Cardiovascular Receptors and Signaling in Heart Failure.
3: Inflammatory Mediators in Heart Failure.
4: Mechanisms of Cardiac Hypertrophy.
5: Hemodynamic Adaptive Mechanisms in Heart Failure.
6: Neurohormonal Axis and Natriuretic Peptides in Heart Failure.
7: Ventricular Pressure–Volume Relationships in Heart Failure.
8: Systolic and Diastolic Function.
9: Echocardiographic Quantitation of Ventricular Function.
10: MRI Assessment of Heart Failure.
11: Assessment of Heart Failure by Invasive Methods.
Clinical Diagnosis and Management of Pediatric Heart Failure.
12: Epidemiology and Economics of Pediatric Heart Failure.
13: Clinical Recognition of Congestive Heart Failure in Children.
14: Classification of Heart Failure.
15: Right Ventricular Dysfunction.
16: Pediatric Myocarditis.
17: Dilated Cardiomyopathy.
18: Clinical Features of Restrictive Cardiomyopathy and Constrictive Pericarditis.
19: Hypertrophic Cardiomyopathy.
20: Left Ventricular Noncompaction Cardiomyopathy.
21: Arrhythmogenic Right Ventricular Cardiomyopathy.
22: Valvular Insufficiency and Heart Failure.
23: Valvular Stenosis and Heart Failure.
24: Ischemic Coronary Artery Disease.
25: Chronic Heart Failure in Congenital Heart Disease Including Single Ventricle Circulation.
26: Heart Failure in Adults With Congenital Heart Disease.
27: Dysrhythmias and Ventricular Dysfunction and Heart Failure.
28: Fetal Heart Failure.
29: Heart Failure in the Neonate.
30: Right Heart Failure in Pediatric Pulmonary Hypertension.
31: Childhood Cardiorenal Syndrome.
32: Heart Failure in Pediatric Oncologic Disease.
33: The Failing Myocardium in Sepsis.
34: Outpatient Management of Pediatric HF.
35: Quality of Life and Psychosocial Care in Pediatric Heart Failure.
36: Quality Metrics and Quality Improvement in Pediatric Heart Failure.
37: Nursing Aspects of Heart Failure.
Medical Treatment for Pediatric Heart Failure.
38: Diuretics and Invasive Fluid Management Strategies.
39: The Use of Inotropic Agents in Acute Decompensated Heart Failure.
40: Phosphodiesterase Inhibitors.
41: Use of Vasodilators in Heart Failure.
42: Section 1. Oral Therapies in the Treatment of Heart Failure in the Young.
43: Section 2. Intravenous Vasodilator Therapies in the Treatment of Heart Failure in the Young.
44: Beta-Adrenergic Receptor Blockade.
45: Recognition and Treatment of Low Cardiac Output States in Pediatric Cardiac Intensive Care.
46: New Therapeutic Strategies in Heart Failure.
47: Electrophysiologic Devices in Heart Failure.
48: Catheter Device Therapies for Heart Failure.
Cardiac Surgery and Pediatric Heart Failure.
49: Posttransplant Heart Failure.
50: Surgical Management of the Failing Systemic Ventricle.
51: Valve Interventions in the Young Adult With Heart Failure.
52: Principles of Mechanical Cardiopulmonary Support.
53: Short-Term Mechanical Cardiopulmonary Support Devices.
54: Decision-Making in Ventricular Assist Device Support in Pediatric Advanced Heart Failure Patients.
55: Long-Term Ventricular Assist Devices in Children.
56: Adult Experience With Long Term Devices.
57: Future of Mechanical Circulatory Support Devices in Children and Young Adults.
Special Topics.
58: Genetic Testing.
59: Data Management and Analytics.
60: Outpatient Monitoring and Self-Care.
61: Regenerative Medicine/Injured Human Hearts.
62: Nanomedicine and Nanotechnology for Heart Failure Research, Diagnosis, and Treatment.
63: Nutritional Assessment and Management in Pediatric Heart Failure.