Dynamics of Proteins and Nucleic Acids, 1st Edition

  • Published By:
  • ISBN-10: 0124116272
  • ISBN-13: 9780124116276
  • DDC: 572.6
  • Grade Level Range: College Freshman - College Senior
  • 368 Pages | eBook
  • Original Copyright 2013 | Published/Released June 2014
  • This publication's content originally published in print form: 2013

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Published continuously since 1944, Advances in Protein Chemistry and Structural Biology has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
Table of Contents.
Introduction to Dynamics of Proteins and Nucleic Acids.
1: Drug–DNA Intercalation: From Discovery to the Molecular Mechanism.
2: Ligand Docking Simulations by Generalized-Ensemble Algorithms.
3: Conformational Dynamics of Single Protein Molecules Studied by Direct Mechanical Manipulation.
4: Generation of Ligand Specificity and Modes of Oligomerization in β-Prism I Fold Lectins.
5: Conformational Changes of Enzymes and DNA in Molecular Dynamics.
6: Protein Functional Dynamics in Multiple Timescales as Studied by NMR Spectroscopy.
7: Protein–DNA Electrostatics Toward a New Paradigm for Protein Sliding.
8: Structural and Dynamical Aspects of HIV-1 Protease and Its Role in Drug Resistance.
Author Index.
Subject Index.