The Neutrophils: New Outlook For Old Cells, 3rd Edition

  • Published By: Imperial College Press
  • ISBN-10: 1848168373
  • ISBN-13: 9781848168374
  • DDC: 612.112
  • Grade Level Range: College Freshman - College Senior
  • 448 Pages | eBook
  • Original Copyright 2013 | Published/Released December 2014
  • This publication's content originally published in print form: 2013

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This is a third edition of the popular book, which presents an overview of the most recent findings in the biology of neutrophils. These cells are critically important for protection against bacterial and viral infections and have been recently demonstrated to be a major contributor to tumor associated immune suppression. In addition, neutrophils represent a unique model for studying fundamental questions of cellular biochemistry and molecular biology. This monograph provides a detailed description of signal transduction, generation of reactive oxygen, and mechanisms of migration and death of these cells. Besides that, it contains unique information regarding neutrophils role in cancer. Finally, this monograph describes recent advances in attempts to improve neutrophil function and use these cells in the treatment of diseases.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
List of Contributors.
1: Molecular Regulation of Granulopoiesis.
2: The Neutrophil Respiratory Burst Oxidase.
3: Novel Neutrophil Receptors and Their Signal Transduction.
4: Mechanisms of Neutrophil Migration.
5: Cytokine Production by Neutrophils.
6: Neutrophils and Apoptosis.
7: Regulation of Neutrophil Functions by Long Chain Fatty Acids.
8: S100 Calgranulins in Inflammation.
9: Neutrophils and Myeloid-Derived Suppressor Cells in Cancer.
10: Colony-Stimulating Factors for Prevention and Treatment of Neutropenia and Infectious Diseases.