Ovarian Toxicology, 2nd Edition

  • Patricia B. Hoyer
  • Published By: CRC Press
  • ISBN-10: 1466504072
  • ISBN-13: 9781466504073
  • DDC: 618.1
  • Grade Level Range: College Freshman - College Senior
  • 392 Pages | eBook
  • Original Copyright 2013 | Published/Released October 2015
  • This publication's content originally published in print form: 2013

  • Price:  Sign in for price



Today, we are exposed to an increasing number of chemicals in the environment and there is a growing awareness of the effects of these chemicals on the ovaries. Infertility resulting from environmental exposures may not be obvious until the reproductive life span is waning. As such, the potential for xenobiotic-induced infertility needs to be better understood.

In recent years, research into chemicals that have the potential to cause early menopause by destroying pre-antral ovarian follicles is gaining greater appreciation. Ovarian Toxicology, Second Edition represents a compilation of chapters prepared by researchers who have substantially contributed to our understanding of the impact of xenobiotics and environmental factors on ovarian function. The second edition substantially updates newly investigated ovotoxicants as well as improved mechanistic insights that have emerged since the first edition.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
Ovarian Function.
1: Ovarian Physiology.
2: Ovarian Metabolism of Xenobiotics.
3: Brain as a Target for Environmental Toxicants that Alter Ovarian Function.
4: Xenobiotic-Induced Oxidative Stress.
5: Ovotoxicity in Small Preantral Follicles.
Ovotoxic Chemical Classes.
6: Ovarian Toxicity Caused by Pesticides.
7: Endocrine Disruptors.
8: Phthalates.
9: Heavy Metals and the Ovary.
10: Cigarette Smoking and Ovarian Function.
11: Bisphenol A and the Ovary.
Ovarian Cancer.
12: Endocrine Effects on Ovarian Cancer: Insight from Animal Models.
13: New Perspectives in Chemoresistant Ovarian Cancer.
14: Ovarian Cancer: A Bioepidemiological Approach.
15: Risk Assessment.
16: Assessing Ovarian Toxicity in Human Health Risk Assessment for Environmental Chemicals and Pharmaceuticals.