Pharmacogenomics, 1st Edition

  • Published By:
  • ISBN-10: 0123983037
  • ISBN-13: 9780123983039
  • DDC: 615.7
  • Grade Level Range: College Freshman - College Senior
  • 510 Pages | eBook
  • Original Copyright 2013 | Published/Released June 2014
  • This publication's content originally published in print form: 2013

  • Price:  Sign in for price



Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward. Clinical pearls and case studies are used to illustrate real-life experiences and both successful and unsuccessful applications. Tables, figures, and annotations are included throughout the book to facilitate understanding and further reference.

Table of Contents

Front Cover.
Half Title Page.
Other Frontmatter.
Title Page.
Copyright Page.
List of Contributors.
1: Principles of Pharmacogenomics: Pharmacokinetic, Pharmacodynamic, and Clinical Implications.
2: Translating Pharmacogenomic Research to Therapeutic Potentials.
3: Governmental and Academic Efforts to Advance the Field of Pharmacogenomics.
4: Pharmacogenomics in Cancer Therapeutics.
5: A Look to the Future: Cancer Epigenetics.
6: Pharmacogenetics in Cardiovascular Diseases.
7: A Look to the Future: Cardiovascular Pharmacoepigenetics Cardiovascular Pharmacoepigenetics.
8: Pharmacogenomics in Psychiatric Disorders.
9: A Look to the Future: Epigenetics in Psychiatric Disorders and Treatment.
10: The Role of Pharmacogenomics in Diabetes, HIV Infection, and Pain Management.
11: Molecular Approaches, Models, and Techniques in Pharmacogenomic Research and Development.
12: Modeling the Pharmacogenetic Architecture of Drug Response.
13: Study Designs in Clinical Pharmacogenetic and Pharmacogenomic Research.
14: Incorporating Pharmacogenomics in Drug Development: A Perspective from Industry.
15: The Importance of Ethnicity Definitions and Pharmacogenomics in Ethnobridging.
16: Beyond ELSIs: Where to from Here? From “Regulating” to Anticipating and Shaping the Innovation Trajectory in Personalized Medicine.
17: Pharmacoeconomics of Pharmacogenetics within the Context of General Health Technology Assessments.
18: Integrating Genomics into Pharmacy Education and Practice: Pharmacogenomics is not Enough.
Color Plates.