Human Herpesviruses HHV-6A, HHV-6B & HHV-7, 3rd Edition

  • Published By:
  • ISBN-10: 0444627162
  • ISBN-13: 9780444627162
  • DDC: 616.925
  • Grade Level Range: College Freshman - College Senior
  • 362 Pages | eBook
  • Original Copyright 2013 | Published/Released June 2014
  • This publication's content originally published in print form: 2013

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Completely revised and updated, Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition, delivers a thorough review of HHV-6, from foundational explorations of classification, molecular biology, and chromosomal integration of the virus to clinical details, including pathologic features of infection, and clinical effects on various organ systems. The work now includes coverage of HHV-7, a virus that remains underestimated in transplant reactivation, seizures, and encephalitis. The book examines the role of HHV-6 in myriad diseases, including cognitive disorders following bone marrow transplant, mesial temporal lobe epilepsy, multiple sclerosis, autoimmune disease, encephalitis, Hodgkin's disease lymphoma (HHV-6B), and glioma (HHV-6A). Descriptions of novel molecular and serological diagnostic assays, along with detailed protocols, are included to aid researchers and clinicians in discriminating potential false positives originating from chromosomally integrated HHV-6 and in differentiating between active and latent infection. Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition is a valuable reference for epidemiologists, virologists, practicing clinicians, infectious disease specialists, pathologists, herpes virus researcher.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
List of Contributors.
Foreword: Part 1.
Foreword: Part 2.
1: HHV-6A and HHV-6B Officially Classified as Distinct Viruses.
2: Practical Diagnostic Procedures for HHV-6A, HHV-6B, and HHV-7.
3: Pathologic Features of HHV-6A, HHV-6B, and HHV-7 Infection (Light and Electron Microscopy).
4: HHV-6A, HHV-6B, and HHV-7 in Febrile Seizures and Status Epilepticus.
5: HHV-6A, HHV-6B, and HHV-7 in Encephalitis.
6: Cognitive Dysfunction from HHV-6A and HHV-6B.
7: HHV-6 and Multiple Sclerosis.
8: Human Herpes Virus 6B in Mesial Temporal Lobe Epilepsy.
9: HHV-6B and HHV-7 in Exanthema Subitum and Related Skin Diseases.
10: HHV-6A and HHV-6B in Autoimmune Disease.
11: HHV-6A and HHV-6B in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms.
12: HHV-6A and HHV-6B in Solid Organ Transplantation.
13: HHV-6A and HHV-6B in Recipients of Hematopoietic Cell Transplantation.
14: The Immune Response to HHV-6.
15: Chromosomally Integrated HHV-6.
16: HHV-6 and HHV-7 in Cardiovascular Diseases and Cardiomyopathies.
17: HHV-6 in Lymphohematopoietic Diseases.
18: HHV-6A and HHV-6B in Cancer.
19: Treating HHV-6 Infections.