Fundamentals of Toxicologic Pathology, 3rd Edition

  • Wanda Haschek
  • Brad Bolon
  • Colin Rousseaux
  • Matthew Wallig
  • Published By:
  • ISBN-10: 0128098422
  • ISBN-13: 9780128098424
  • DDC: 615.9
  • Grade Level Range: College Freshman - College Senior
  • 902 Pages | eBook
  • Original Copyright 2018 | Published/Released May 2018
  • This publication's content originally published in print form: 2018

  • Price:  Sign in for price



This wholly revised and updated edition presents the newest information on the topic of systems toxicologic pathology, which integrates toxicology and its interdisciplinary components, including biochemistry, pharmacodynamics and risk assessment to pathology and its related disciplines, such as physiology, microbiology, immunology and molecular biology. It includes a new section describing the application of toxicologic pathology, such as diagnostic and forensic toxicologic pathology, environmental toxicologic pathology, experimental and industrial toxicologic pathology, and pathology issues in the design of toxicology studies. There are also new chapters on special senses (the eye and ear) and the biochemical and molecular basis of toxicity, among others.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
Other Frontmatter.
List of Contributors.
1: An Overview of Toxicologic Pathology.
Principles of Toxicologic Pathology.
2: Biochemical and Molecular Basis of Toxicity.
3: Pharmacokinetics and Toxicokinetics.
4: Principles of Pharmacodynamics and Toxicodynamics.
5: Morphologic Manifestations of Toxic Cell Injury.
6: Carcinogenesis: Manifestation and Mechanisms.
7: Design of Studies and Risk Management in Toxicologic Pathology: Addressing Risks in Product Discovery and Development.
Systems Toxicologic Pathology.
8: Liver and Gall Bladder.
9: Cardiovascular System.
10: Skeletal Muscle System.
11: Urinary System.
12: Immune System.
13: Hematopoietic System.
14: Respiratory System.
15: Digestive System.
16: Exocrine Pancreas.
17: Male Reproductive System.
18: Female Reproductive System.
19: The Mammary Gland.
20: Endocrine System.
21: Nervous System.
22: Special Senses.
23: Special Senses—Eye.
24: Special Senses—Ear.
25: Bone and Joints.
26: The Integumentary System.
27: Embryo, Fetus, and Placenta.