Receptor-Receptor Interactions, 1st Edition

  • Published By:
  • ISBN-10: 0124104703
  • ISBN-13: 9780124104709
  • DDC: 571.64
  • Grade Level Range: College Freshman - College Senior
  • 538 Pages | eBook
  • Original Copyright 2013 | Published/Released June 2014
  • This publication's content originally published in print form: 2013

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This new volume of Methods in Cell Biology looks at receptor-receptor interactions, with sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes. With cutting-edge material, this comprehensive collection is intended to guide researchers of receptor-receptor interactions for years to come.

Table of Contents

Front Cover.
Half Title Page.
Other Frontmatter.
Title Page.
Copyright Page.
1: Spatial Intensity Distribution Analysis (SpIDA): A New Tool for Receptor Tyrosine Kinase Activation and Transactivation Quantification.
2: Dimerization of Nuclear Receptors.
3: Network Analysis to Uncover the Structural Communication in GPCRs.
4: Simulating G Protein-Coupled Receptors in Native-Like Membranes: from Monomers to Oligomers.
5: Structure-Based Molecular Modeling Approaches to GPCR Oligomerization.
6: Biochemical and Imaging Methods to Study Receptor Membrane Organization and Association with Lipid Rafts.
7: Serotonin Type 4 Receptor Dimers.
8: Bioluminescence Resonance Energy Transfer Methods to Study G Protein-Coupled Receptor–Receptor Tyrosine Kinase Heteroreceptor Complexes.
9: A Simple Method to Detect Allostery in GPCR Dimers.
10: Fluorescence Correlation Spectroscopy and Photon-Counting Histogram Analysis of Receptor–Receptor Interactions.
11: Monitoring Receptor Oligomerization by Line-Scan Fluorescence Cross-Correlation Spectroscopy.
12: Biochemical Assay of G Protein-Coupled Receptor Oligomerization: Adenosine A1 and Thromboxane A2 Receptors form the Novel Functional Hetero-Oligomer.
13: Oligomerization of Sweet and Bitter Taste Receptors.
14: Analysis of Receptor–Receptor Interaction by Combined Application of FRET and Microscopy.
15: Site-Specific Labeling of Genetically Encoded Azido Groups for Multicolor, Single-Molecule Fluorescence Imaging of GPCRs.
16: Analysis of EGF Receptor Oligomerization by Homo-FRET.
17: Detection of G Protein-Coupled Receptor (GPCR) Dimerization by Coimmunoprecipitation.
18: Lipid-Dependent GPCR Dimerization.
19: Monitoring Peripheral Protein Oligomerization on Biological Membranes.
20: Single-Molecule Imaging of Receptor–Receptor Interactions.
21: Visualization of TCR Nanoclusters via Immunogold Labeling, Freeze-Etching, and Surface Replication.
22: Identification of Multimolecular Complexes and Supercomplexes in Compartment-Selective Membrane Microdomains.
23: G Protein-Coupled Receptor Transactivation.
24: Crystallization of G Protein-Coupled Receptors.
Volumes in Series.
Color Plate.