Skin Tissue Models for Regenerative Medicine, 1st Edition

  • Alexandra Marques
  • Rui Reis
  • Rogério Pirraco
  • Mariana Cerqueira
  • Published By:
  • ISBN-10: 0128110007
  • ISBN-13: 9780128110003
  • DDC: 612.79
  • Grade Level Range: College Freshman - College Senior
  • 472 Pages | eBook
  • Original Copyright 2018 | Published/Released June 2018
  • This publication's content originally published in print form: 2018

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This volume provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. It offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies.

The editors have created a table of contents which frames the relevance of skin tissue models for researchers as platforms to study skin biology and therapeutic approaches for different skin diseases, for clinicians as tissue substitutes, and for cosmetic and pharmaceutical industries as alternative test substrates that can replace animal models.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
Therapeutic molecules and cosmetics testing.
1: Cosmetic industry requirements regarding skin models for cosmetic testing.
2: Overall perspective on the clinical importance of skin models.
Skin diseases: Clinical demands and diseased-skin in vitro models.
3: In vitro models of melanoma.
4: Organotypic and humanized animal models of genodermatoses.
5: In Vitro Models of Psoriasis.
6: In vitro models of vitiligo.
7: Skin squamous cell carcinoma models: The role in combating the disease.
Skin Substitutes: Clinical Demands and Skin Tissue Equivalents.
8: Strategies to Promote the Vascularization of Skin Substitutes After Transplantation.
9: Wound healing and cutaneous scarring models of the human skin.
10: Preclinical models for wound-healing studies.
11: The importance of targeting inflammation in skin regeneration.
In Vitro Models as study platforms of skin Biology.
12: In vitro models to study hair follicle generation.
13: In vitro models to study cutaneous innervation mechanisms.
14: Skin in vitro models to study dermal white adipose tissue role in skin healing.
15: Immunocompetent human in vitro skin models.
Emerging Technologies for the Development of 3D Skin Models.
16: Additive Manufacturing in the Development of 3D Skin Tissues.
17: Induced Pluripotent Stem Cells to Generate Skin Tissue Models.
18: Requirements of Skin Tissue Models for High-Throughput Screening.