Structural Aspects Of Protein Synthesis, 2nd Edition

  • Published By: World Scientific Publishing Company
  • ISBN-10: 981431322X
  • ISBN-13: 9789814313223
  • DDC: 572.6
  • Grade Level Range: College Freshman - College Senior
  • 492 Pages | eBook
  • Original Copyright 2013 | Published/Released December 2014
  • This publication's content originally published in print form: 2013

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This highly illustrated book provides an up-to-date description of the structure and function of the translation system including ribosomes, tRNAs, translation factors, antibiotics and aminoacyl-tRNA synthetases.Research on translation is undergoing rapid changes and is receiving significant attention as evidenced by the Nobel Prize in Chemistry 2009. The structural research by crystallography and cryo-EM forms part of an interactive framework that involves biochemistry and molecular computation. The book provides a comprehensive overview of translation in light of the structural results. It is a valuable resource for scientists in this and related fields, as well as for students taking courses with a focus on translation.There is no other book in this field currently except the previous edition of this book. The authors have for a long time worked in the field of structure and function of the translation system.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
1: The Basics of Translation.
2: Historical Milestones.
3: Methods of Studying Structure.
4: The Message — mRNA.
5: The Adaptor — tRNA.
6: The Workbench — Ribosomes.
7: The Structure of the Ribosome.
8: Ribosomal Sites and Ribosomal States.
9: Colorplates.
10: The Catalysts — Translation Factors.
11: Inhibitors of Protein Synthesis — Antibiotics, Resistance.
12: The Process — Translation.
13: Protein Processing, Folding and Targeting.
14: Evolution of the Translation Apparatus.
Appendix I.
Appendix II.