Genomic and Precision Medicine: Foundations, Translation, and Implementation, 3rd Edition

  • Geoffrey Ginsburg
  • Huntington Willard
  • Published By:
  • ISBN-10: 0128006560
  • ISBN-13: 9780128006566
  • DDC: 616.042
  • Grade Level Range: College Freshman - College Senior
  • 398 Pages | eBook
  • Original Copyright 2017 | Published/Released May 2017
  • This publication's content originally published in print form: 2017

  • Price:  Sign in for price



This book highlights the various points along the continuum from health to disease where genomic information is impacting clinical decision-making and leading to more personalization of health care. It pinpoints the challenges, barriers, and solutions that have been, or are being, brought forward to enable translation of genome based technologies into health care. A variety of infrastructure (data systems and EMRs), policy (regulatory, reimbursement, privacy), and research (comparative effectiveness research, learning health system approaches) strategies are also discussed. Readers will find this volume to be an invaluable resource for the translational genomics and implementation science that is required to fully realize personalized health care.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
List of Contributors.
1: The Human Genome: Foundation for Genomic and Precision Medicine.
2: The Functional Genome: Epigenetics and Epigenomics.
3: The State of Whole-Genome Sequencing.
4: The Human Microbiome.
5: Quantitative Proteomics for Clinical Translation.
6: From Data to Knowledge: An Introduction to Biomedical Informatics.
7: Local and Global Challenges in the Clinical Implementation of Precision Medicine.
8: From Biobanking to Precision Medicine: The Estonian Experience.
9: Electronic Health Records and Genomic Medicine.
10: Data Sharing and Privacy.
11: Designing Genetic- and Genomic-Based Clinical Trials.
12: Developing the Evidence to Support Clinical Use of Genomics.
13: Family Health History and Health Risk Assessment in Health Care.
14: Genetics Aware Clinical Decision Support.
15: Implementation Science and Integration into Healthcare Systems.
16: Pharmacogenetics and Pharmacogenomics.
17: Clinical Genomic Testing.
18: Molecular Genetic Testing and the Future of Clinical Genomics.
19: Bringing Genomics to Medicine: Ethical, Policy, and Social Considerations.
20: Educational Issues and Strategies for Genomic Medicine: For the Public and for Providers.
21: Regulation of Genomic Technologies.
22: Developing the Value Proposition for Personalized Medicine.
23: Technology Assessment and the Road to Reimbursement of Genomic Based Diagnostics.
24: Legal Issues in Genomic and Precision Medicine: Intellectual Property and Beyond.