NEW

eBook MR and CT Perfusion and Pharmacokinetic Imaging: Clinical Applications and Theory, 1st Edition

  • Published By: Lippincott Williams & Wilkins
  • ISBN-10: 1469889625
  • ISBN-13: 9781469889627
  • DDC: 616.07
  • Grade Level Range: College Freshman - College Senior
  • 1004 Pages | eBook
  • Original Copyright 2015 | Published/Released March 2017
  • This publication's content originally published in print form: 2015
  • Price:  Sign in for price

About

Overview

The long-awaited first edition of MR And CT Perfusion And Pharmacokinetic Imaging: Clinical Applications And Theory is a welcome new resource for healthcare professionals involved in the rapidly evolving field of perfusion technology. Using MRI and CT scanning procedures, perfusion imaging is being used with increasing frequency to aid the diagnostic process in a wide spectrum of pathologies, including ischemia, cancer, inflammation and many more, throughout the entire human body. This is the first text of its kind to comprehensively address the technical and clinical aspects of perfusion imaging, used in both MRI and CT.

Table of Contents

Front Cover.
Title Page.
Copyright Page.
Dedication.
Contributors.
Foreword (Neuroimaging).
Foreword (Body Imaging).
Preface.
Contents.
Theory.
1: Instrumentation & Basics.
2: Primer on CT Physics and Hardware.
3: CT Image Reconstruction Basics.
4: Dose Considerations in CT Perfusion.
5: Clinical Applications and Theoretical Principles: Primer on Physics of MR and Hardware.
6: MR Image Reconstruction.
7: MR Relaxation Theory and Exchange Processes in the Presence of Contrast Agents.
8: MR and CT Contrast Agents for Perfusion Imaging and Regulatory Issues.
9: Contrast Agent Safety and Nephrogenic Systemic Fibrosis.
10: CT Perfusion Imaging.
11: Acquisition Schemes for Computed Tomography Perfusion.
12: Xe-Enhanced CT Perfusion Measurements.
13: Dynamic Susceptibility Contrast-Based PWI.
14: Susceptibility Contrast in Tissues: Gradient Echoes Versus Spin Echoes.
15: Magnetic Resonance Pulse Sequences for Dynamic Susceptibility Contrast.
16: Vessel Size Imaging.
17: Oxygen Extraction Fraction (OEF) Imaging.
18: Arterial Spin Labeling.
19: Basic Principles of Arterial Spin Labeling: Continuous Versus Pulsed Arterial Spin Labeling.
20: Readout and Background Suppression Techniques.
21: Pseudo-Continuous Arterial Spin Labeling.
22: Confounding Effects in Arterial Spin Labeling.
23: Flow Territory Mapping: Region-Selective Arterial Spin Labeling.
24: Velocity-Selective Arterial Spin Labeling.
25: Keys to Robust Arterial Spin Labeling in the Clinical and Research Environment.
26: “Pick Your Poison”: The Arterial Spin Labeling Shopper’s Guide or Which Method for Which Application?.
27: Dynamic Contrast-Enhanced MR and CT.
28: The Basic Principles of Dynamic Contrast–Enhanced Magnetic Resonance Imaging.
29: Computational Methods.
30: Convolution Model.
31: Practical Aspects of Deconvolution.
32: Arterial Input Function and Venous Output Function.
33: The Bookend Technique and Other Scaling Techniques.
34: The Effects of Contrast Agent Extravasation Perfusion Parameter Maps Derived From Dynamic Susceptibility Contrast Magnetic Resonance Imaging.
35: Pharmacokinetic Models for Dynamic Contrast-Enhanced Computed Tomography and Magnetic Resonance Imaging.
36: Blood Flow Quantitation With Arterial Spin Labeling.
37: Perfusion Confusion: What is Perfusion and What Do We Measure?.
38: Comparability.
39: Dynamic Susceptibility Contrast Magnetic Resonance Imaging Calibration Between Sites and Comparability.
40: CT Perfusion Imaging: Calibration and Comparability.
41: Arterial Spin Labeling Calibration Between Sites and Comparability.
42: Dynamic Contrast-Enhanced Magnetic Resonance Imaging Calibration Between Sites and Comparability.
Clinical Applications.
43: Setting the Stage.
44: Normal Blood Flow Values in Organs.
45: Information About MR and CT Contrast Agents.
46: General Patient Dressing for Magnetic Resonance and Computed Tomography Studies.
47: Arterial Spin Labeling Acquisition Protocols.
48: Cerebrovascular Diseases.
49: Cerebrovascular Anatomy and Regional Blood Supply.
50: Normal and Abnormal Physiology of Cerebral Blood Flow.
51: Acute Stroke: Intra-Arterial and Intravenous Treatment Options.
52: Perfusion Profiles for Favorable and Unfavorable Outcomes.
53: Collateral Flow, Luxury Perfusion, and Vasospasm: Clinical Applications and Theoretical Principles.
54: The Role of Multimodal Brain Imaging in Clinical Stroke Trials.
55: Lacunar Stroke and Microangiopathy.
56: Perfusion and Dynamic Contrast-Enhanced Imaging in Hemorrhage.
57: Perfusion Imaging in Chronic Occlusive Disease of Intracranial Vessels and Vascular Reserve Testing.
58: Perfusion in Chronic Carotid Artery Disease.
59: Transient Ischemic Attack and Perfusion Imaging.
60: Arterial Spin Labeling in Arteriovenous Malformations.
61: Perfusion in Dural Arteriovenous Fistulas.
62: Migraine and Seizures.
63: Pediatric Stroke and Congenital Disease.
64: Tumors.
65: Tumor Vasculature: Structure and Function.
66: Response Evaluation Criteria in Solid Tumors (RECIST) and World Health Organization (WHO) Criteria for Cancer Progression.
67: De Novo Brain Tumor Evaluation: Use of Individual and Combined DSC, DCE, and ASL for Diagnosis and Differentiation.
68: Predicting Prognosis, Therapy Selection, Guidance, and Treatment Monitoring.
69: Contrast Enhancement: Differentiating Tumor Recurrence From Non-Neoplastic Tissue Following Intervention (Surgery, Chemotherapy, Radiotherapy).
70: Perfusion Imaging Using Magnetic Resonance Imaging and Computed Tomography in Head and Neck Cancer.
71: Female Pelvis.
72: Lung Cancer.
73: Breast Cancer.
74: Prostate Cancer.
75: Perfusion Imaging in Liver and Pancreas.
76: Renal Tumors.
77: Gastrointestinal Imaging.
78: Clinical Applications of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Musculoskeletal Tumors.
79: Oncology Drug Development.
80: Myocardial Perfusion and Permeability.
81: Miscellaneous.
82: Dementia and Degenerative Diseases.
83: Perfusion in Pharmacologic Imaging.
84: Perfusion and Dynamic Contrast-Enhanced Imaging in White Matter Disease.
85: Cerebral Perfusion Studies in Substance Abuse and Dependence.
86: Perfusion and Dynamic Contrast-Enhanced Imaging to Study Renal Function.
87: Arterial Spin Labeling for Functional Neuroimaging.
88: Vascular Response to Hypoxia and Hypercapnia.
89: Retinal and Choroidal Blood Flow.
90: Vascular-Space-Occupancy Magnetic Resonance Imaging.
91: History.
92: Computed Tomography Perfusion Imaging: How Did It All Start?.
93: The History of Dynamic Susceptibility Contrast Imaging: An Interview With Roland Bammer.
94: The Early History of Arterial Spin Labeling Magnetic Resonance Imaging: 1992 to 2000.
95: The Early Days of Modeling Contrast Agent Kinetics.
Index.
Front Cover.
Title Page.
Copyright Page.
Dedication.
Contributors.
Foreword (Neuroimaging).
Foreword (Body Imaging).
Preface.
Contents.
Theory.
1: Instrumentation & Basics.
2: Primer on CT Physics and Hardware.
3: CT Image Reconstruction Basics.
4: Dose Considerations in CT Perfusion.
5: Clinical Applications and Theoretical Principles: Primer on Physics of MR and Hardware.
6: MR Image Reconstruction.
7: MR Relaxation Theory and Exchange Processes in the Presence of Contrast Agents.
8: MR and CT Contrast Agents for Perfusion Imaging and Regulatory Issues.
9: Contrast Agent Safety and Nephrogenic Systemic Fibrosis.
10: CT Perfusion Imaging.
11: Acquisition Schemes for Computed Tomography Perfusion.
12: Xe-Enhanced CT Perfusion Measurements.
13: Dynamic Susceptibility Contrast-Based PWI.
14: Susceptibility Contrast in Tissues: Gradient Echoes Versus Spin Echoes.
15: Magnetic Resonance Pulse Sequences for Dynamic Susceptibility Contrast.
16: Vessel Size Imaging.
17: Oxygen Extraction Fraction (OEF) Imaging.
18: Arterial Spin Labeling.
19: Basic Principles of Arterial Spin Labeling: Continuous Versus Pulsed Arterial Spin Labeling.
20: Readout and Background Suppression Techniques.
21: Pseudo-Continuous Arterial Spin Labeling.
22: Confounding Effects in Arterial Spin Labeling.
23: Flow Territory Mapping: Region-Selective Arterial Spin Labeling.
24: Velocity-Selective Arterial Spin Labeling.
25: Keys to Robust Arterial Spin Labeling in the Clinical and Research Environment.
26: “Pick Your Poison”: The Arterial Spin Labeling Shopper’s Guide or Which Method for Which Application?.
27: Dynamic Contrast-Enhanced MR and CT.
28: The Basic Principles of Dynamic Contrast–Enhanced Magnetic Resonance Imaging.
29: Computational Methods.
30: Convolution Model.
31: Practical Aspects of Deconvolution.
32: Arterial Input Function and Venous Output Function.
33: The Bookend Technique and Other Scaling Techniques.
34: The Effects of Contrast Agent Extravasation Perfusion Parameter Maps Derived From Dynamic Susceptibility Contrast Magnetic Resonance Imaging.
35: Pharmacokinetic Models for Dynamic Contrast-Enhanced Computed Tomography and Magnetic Resonance Imaging.
36: Blood Flow Quantitation With Arterial Spin Labeling.
37: Perfusion Confusion: What is Perfusion and What Do We Measure?.
38: Comparability.
39: Dynamic Susceptibility Contrast Magnetic Resonance Imaging Calibration Between Sites and Comparability.
40: CT Perfusion Imaging: Calibration and Comparability.
41: Arterial Spin Labeling Calibration Between Sites and Comparability.
42: Dynamic Contrast-Enhanced Magnetic Resonance Imaging Calibration Between Sites and Comparability.
Clinical Applications.
43: Setting the Stage.
44: Normal Blood Flow Values in Organs.
45: Information About MR and CT Contrast Agents.
46: General Patient Dressing for Magnetic Resonance and Computed Tomography Studies.
47: Arterial Spin Labeling Acquisition Protocols.
48: Cerebrovascular Diseases.
49: Cerebrovascular Anatomy and Regional Blood Supply.
50: Normal and Abnormal Physiology of Cerebral Blood Flow.
51: Acute Stroke: Intra-Arterial and Intravenous Treatment Options.
52: Perfusion Profiles for Favorable and Unfavorable Outcomes.
53: Collateral Flow, Luxury Perfusion, and Vasospasm: Clinical Applications and Theoretical Principles.
54: The Role of Multimodal Brain Imaging in Clinical Stroke Trials.
55: Lacunar Stroke and Microangiopathy.
56: Perfusion and Dynamic Contrast-Enhanced Imaging in Hemorrhage.
57: Perfusion Imaging in Chronic Occlusive Disease of Intracranial Vessels and Vascular Reserve Testing.
58: Perfusion in Chronic Carotid Artery Disease.
59: Transient Ischemic Attack and Perfusion Imaging.
60: Arterial Spin Labeling in Arteriovenous Malformations.
61: Perfusion in Dural Arteriovenous Fistulas.
62: Migraine and Seizures.
63: Pediatric Stroke and Congenital Disease.
64: Tumors.
65: Tumor Vasculature: Structure and Function.
66: Response Evaluation Criteria in Solid Tumors (RECIST) and World Health Organization (WHO) Criteria for Cancer Progression.
67: De Novo Brain Tumor Evaluation: Use of Individual and Combined DSC, DCE, and ASL for Diagnosis and Differentiation.
68: Predicting Prognosis, Therapy Selection, Guidance, and Treatment Monitoring.
69: Contrast Enhancement: Differentiating Tumor Recurrence From Non-Neoplastic Tissue Following Intervention (Surgery, Chemotherapy, Radiotherapy).
70: Perfusion Imaging Using Magnetic Resonance Imaging and Computed Tomography in Head and Neck Cancer.
71: Female Pelvis.
72: Lung Cancer.
73: Breast Cancer.
74: Prostate Cancer.
75: Perfusion Imaging in Liver and Pancreas.
76: Renal Tumors.
77: Gastrointestinal Imaging.
78: Clinical Applications of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Musculoskeletal Tumors.
79: Oncology Drug Development.
80: Myocardial Perfusion and Permeability.
81: Miscellaneous.
82: Dementia and Degenerative Diseases.
83: Perfusion in Pharmacologic Imaging.
84: Perfusion and Dynamic Contrast-Enhanced Imaging in White Matter Disease.
85: Cerebral Perfusion Studies in Substance Abuse and Dependence.
86: Perfusion and Dynamic Contrast-Enhanced Imaging to Study Renal Function.
87: Arterial Spin Labeling for Functional Neuroimaging.
88: Vascular Response to Hypoxia and Hypercapnia.
89: Retinal and Choroidal Blood Flow.
90: Vascular-Space-Occupancy Magnetic Resonance Imaging.
91: History.
92: Computed Tomography Perfusion Imaging: How Did It All Start?.
93: The History of Dynamic Susceptibility Contrast Imaging: An Interview With Roland Bammer.
94: The Early History of Arterial Spin Labeling Magnetic Resonance Imaging: 1992 to 2000.
95: The Early Days of Modeling Contrast Agent Kinetics.
Index.