eBook G Protein-Coupled Receptors in Energy Homeostasis and Obesity Pathogenesis, 1st Edition

  • Published By:
  • ISBN-10: 0123869528
  • ISBN-13: 9780123869524
  • DDC: 616.398042
  • Grade Level Range: College Freshman - College Senior
  • 400 Pages | eBook
  • Original Copyright 2013 | Published/Released June 2014
  • This publication's content originally published in print form: 2013
  • Price:  Sign in for price

About

Overview

Obesity is an epidemic with enormous health, economic and social burdens. Current drugs for obesity treatment are far from ideal in terms of efficacy and side effects. Reviews in this volume of Progress in Molecular Biology and Translational Science summarize current status in studies of a number of G protein-coupled receptors that were shown to be promising targets for obesity treatments. Some of these receptors also cause monogenic obesity in humans. Subject matter: obesity is an epidemic and G protein-coupled receptors are promising drug targets, with significant potential as new anti-obesity drugs. Chapters are written by leading experts.

Table of Contents

Front Cover.
Half Title.
Title Page.
Copyright.
Contents.
Contributors.
Preface.
1: G Protein-Coupled Receptors as Regulators of Energy Homeostasis.
2: Ghrelin Receptor in Energy Homeostasis and Obesity Pathogenesis.
3: Obestatin Receptor in Energy Homeostasis and Obesity Pathogenesis.
4: Melanocortin-3 Receptors and Metabolic Homeostasis.
5: Melanocortin-4 Receptor in Energy Homeostasis and Obesity Pathogenesis.
6: G Protein-Coupled Estrogen Receptor in Energy Homeostasis and Obesity Pathogenesis.
7: Free Fatty Acid Receptor GPR120 and Pathogenesis of Obesity and Type 2 Diabetes Mellitus.
8: The Role of Cholecystokinin Receptors in the Short-Term Control of Food Intake.
9: Adiponectin Receptors in Energy Homeostasis and Obesity Pathogenesis.
10: The Role of Bombesin and Bombesin-Related Peptides in the Short-term Control of Food Intake.
Index.
Other Backmatter.