eBook Genetic Damage in Human Spermatozoa, 1st Edition

  • Published By:
  • ISBN-10: 1461477832
  • ISBN-13: 9781461477839
  • DDC: 571.9
  • Grade Level Range: College Freshman - College Senior
  • 195 Pages | eBook
  • Original Copyright 2014 | Published/Released April 2015
  • This publication's content originally published in print form: 2014
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About

Overview

There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.

Table of Contents

Front Cover.
Editorial Board.
Title Page.
Copyright Page.
Dedication Page.
Preface.
Contents.
Contributors.
1: Structure of Chromatin in Spermatozoa.
2: Genomic Changes in Spermatozoa of the Aging Male.
3: Chromosomal Aberrations and Aneuploidies of Spermatozoa.
4: The Sperm Epigenome: Implications for the Embryo.
5: Environmental Epigenetics and Effects on Male Fertility.
6: Protamine Alterations in Human Spermatozoa.
7: Sperm DNA Fragmentation and Base Oxidation.
8: Iatrogenic Genetic Damage of Spermatozoa.
9: Sperm Cryopreservation: Effects on Chromatin Structure.
10: Sperm Selection: Effect on Sperm DNA Quality.
11: Effect of Antioxidants on Sperm Genetic Damage.
12: Erratum to: Structure of Chromatin in Spermatozoa.
Index.
Front Cover.
Editorial Board.
Title Page.
Copyright Page.
Dedication Page.
Preface.
Contents.
Contributors.
1: Structure of Chromatin in Spermatozoa.
2: Genomic Changes in Spermatozoa of the Aging Male.
3: Chromosomal Aberrations and Aneuploidies of Spermatozoa.
4: The Sperm Epigenome: Implications for the Embryo.
5: Environmental Epigenetics and Effects on Male Fertility.
6: Protamine Alterations in Human Spermatozoa.
7: Sperm DNA Fragmentation and Base Oxidation.
8: Iatrogenic Genetic Damage of Spermatozoa.
9: Sperm Cryopreservation: Effects on Chromatin Structure.
10: Sperm Selection: Effect on Sperm DNA Quality.
11: Effect of Antioxidants on Sperm Genetic Damage.
12: Erratum to: Structure of Chromatin in Spermatozoa.
Index.