Half Title Page.
About the Editors.
1: Blood Banking and Transfusion Medicine.
2: Blood Banking and Transfusion Medicine – History, Industry, and Discipline.
3: Quality Principles in Transfusion Medicine.
4: Regulatory Issues in Transfusion Medicine.
5: Role of the Physician in the Blood Center.
6: Blood Donor, Donation Process and Technical Aspects of Blood Collection.
7: Apheresis Blood Component Collections.
8: Recipient-Specific Blood Donation.
9: Adverse Donor Reactions.
10: Component Preparation and Manufacturing.
11: Serologic Testing of Donor Products.
12: Overview of Infectious Disease Testing.
13: Human Immunodeficiency Virus Screening.
14: Hepatitis B Viral Screening.
15: Hepatitis C Virus Screening.
16: West Nile Virus Screening.
17: Syphilis, Human T-Cell Lymphotropic Virus, and Chagas Screening.
18: Bacterial Detection Methods.
19: Role of the Transfusion Service Physician.
20: Pretransfusion Testing.
21: Antibody Identification.
22: Direct Antiglobulin Test.
23: Molecular DNA Based Blood Group Typing.
24: ABO and H Blood Group System.
25: Rh and RhAG Blood Group Systems.
26: Kell and Kidd Blood Group Systems.
27: MNS and Duffy Blood Group Systems.
28: Lewis, I, P1PK and GLOB Blood Group Systems.
29: Other Blood Group Systems, Collections, and Series.
30: Human Platelet Antigens.
31: HLA Antigens.
32: Red Blood Cell Products.
33: Plasma Products.
34: Platelet Products.
35: Cryoprecipitate and Fibrinogen Concentrates.
36: Granulocyte Products.
37: Albumin and Related Products.
38: Human Immunoglobulin Preparations.
39: Rh Immune Globulin.
40: Coagulation Factor Products.
41: Irradiation of Blood Products.
42: Leukoreduction of Blood Products.
43: CMV-Safe Blood Products.
44: Frozen Blood Products.
45: Washed Blood Products.
46: Volume Reduced Products.
47: Pathogen Reduction Technologies.
48: Neonatal and Pediatric Transfusion Medicine.
49: Perinatal Transfusion Medicine.
50: Autoimmune Hemolytic Anemias.
51: Transfusion Management in Patients with Hemoglobinopathies.
52: Transfusion of Patients Undergoing Hematopoietic Stem Cell and Solid Organ Transplantation.
53: Transfusion Management of Patients Receiving Antithrombotic Therapy.
54: Blood Transfusion in Economically Restricted and Developing Countries.
55: Management of Patients Who Refuse Blood Transfusion.
56: Platelet Transfusion Refractory Patients.
57: Massive Transfusion.
58: Patient Blood Management.
59: Overview of Adverse Events and Outcomes Following Transfusion.
60: Febrile Non-Hemolytic Transfusion Reactions.
61: Allergic Transfusion Reactions.
62: Acute Hemolytic Transfusion Reactions.
63: Delayed Hemolytic Transfusion Reactions.
64: Transfusion-Associated Circulatory Overload.
65: Transfusion-Related Acute Lung Injury.
66: Septic Transfusion Reactions.
67: Metabolic, Hypotensive and Other Acute Reactions and Complications.
68: Post-Transfusion Purpura.
69: Transfusion-Associated Graft-Versus-Host Disease.
70: Transfusion-Related Immunomodulation.
71: Iron Overload.
72: Transfusion-Transmitted Diseases.
73: Overview of Therapeutic Apheresis.
74: Therapeutic Plasma Exchange.
75: Therapeutic Erythrocytapheresis.
76: Therapeutic Thrombocytapheresis.
77: Therapeutic Leukocytapheresis and Adsorptive Cytapheresis.
78: Extracorporeal Photopheresis.
79: LDL Apheresis.
81: Therapeutic Phlebotomy.
82: Overview of Cellular Therapy.
83: Hematopoietic Progenitor Cell Products Derived from Bone Marrow and Peripheral Blood.
84: Cord Blood Banking.
85: Regenerative Medicine.
86: Tissue Banking in the Hospital Setting.
87: Adverse Events Associated with Hematopoietic Progenitor Cell Product Infusion.
88: Quality and Regulatory Issues in Cellular Therapy.
90: Overview of the Coagulation System.
91: Approach to the Bleeding Patient.
92: Congenital Thrombocytopenia.
93: Fetal and Neonatal Alloimmune Thrombocytopenia.
94: Acquired Neonatal Thrombocytopenia.
95: Bernard-Soulier Syndrome and Other GPIb-IX–V Related Receptor Defects.
96: Glanzmann Thrombasthenia.
97: Platelet Storage Granule Defects.
98: Failure to Release and Aspirin-like Defects.
99: Acute (Childhood) Immune Thrombocytopenia.
100: Chronic Immune Thrombocytopenia.
101: Drug-Induced Thrombocytopenia.
102: Heparin-Induced Thrombocytopenia.
103: Autoimmune Lymphoproliferative Syndrome.
104: Hemolytic Uremic Syndrome.
105: Thrombotic Thrombocytopenic Purpura.
106: Antiphospholipid Syndrome.
107: von Willebrand Disease.
108: Hemophilia A.
109: Hemophilia B.
110: Congenital Disorders of Fibrinogen.
111: Factor XIII, α2-Antiplasmin and Plasminogen Activator Inhibitor-1 Deficiencies.
112: Factor XI Deficiency.
113: Factor VII Deficiency.
114: Factor II, Factor V and Factor X Deficiencies.
115: Bleeding Disorders in Pregnancy.
116: Vascular Bleeding Disorders.
117: Bleeding Risks with Liver Disease.
118: Bleeding Risks with Vitamin K Deficiency.
119: Bleeding Risks with Cardiac Disease.
120: Bleeding Risks with Renal Disease.
121: Bleeding Disorders in Cancer Patients.
122: Disseminated Intravascular Coagulopathy.
123: Acquired Coagulation Factor Inhibitors.
124: Overview of Purposes of Hemostasis Testing and Common Sources of Error.
125: Thrombin Time and Fibrinogen Determination.
126: Prothrombin Time.
127: Activated Partial Thromboplastin Time.
128: Mixing Studies.
129: Coagulation Factor Testing.
130: Specific Factor Inhibitor Testing.
131: Laboratory Diagnosis of Lupus Anticoagulant and Anti-Phospholipid Antibodies.
132: Laboratory Diagnosis of Inherited von Willebrand Disease.
133: Laboratory Diagnosis of Acquired von Willebrand Syndrome.
134: Laboratory Assessment of Treatment of von Willebrand Disease.
135: Measurement of Platelet Count, Mean Platelet Volume and Reticulated Platelets.
136: Platelet Function Analyzer.
137: Platelet Aggregation Studies.
138: Laboratory Diagnosis of Platelet Function Defects.
139: Antiplatelet Therapy Monitoring.
140: Laboratory Diagnosis of Heparin-Induced Thrombocytopenia.
141: Laboratory Evaluation of Thrombotic Thrombocytopenic Purpura.
142: Fibrinolytic Testing.
143: Laboratory Evaluation of Factor XIII Deficiency.
144: Laboratory Techniques in Fibrinolysis Testing.
145: Laboratory Evaluation of Long-Term Thrombophilic Disorders.
146: Antithrombin Testing.
147: Protein C Deficiency Evaluation.
148: Protein S Deficiency Evaluation.
149: Testing for Activated Protein C Resistance.
150: Molecular Testing for Factor V Leiden and Prothrombin Gene Mutations in Inherited Thrombophilia.
151: Laboratory Management of Disseminated Intravascular Coagulation.
152: Circulating Microparticles.
153: Monitoring of Heparins, Fondaparinux, Direct Thrombin Inhibitors and Oral Anti-Xa Medications.
154: Laboratory Support for Warfarin Monitoring.
155: Thrombin Generation Assays.
General Handbook References.