eBook A New Era of Catecholamines in the Laboratory and Clinic, 1st Edition

  • Published By:
  • ISBN-10: 012411539X
  • ISBN-13: 9780124115392
  • DDC: 615.3
  • Grade Level Range: College Freshman - College Senior
  • 512 Pages | eBook
  • Original Copyright 2013 | Published/Released June 2014
  • This publication's content originally published in print form: 2013
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About

Overview

This new volume of Advances in Pharmacology presents catecholamine symposium proceedings. Chapters cover such topics as cellular dynamics of catecholamine release and re-uptake, catecholamines in mood regulation and imaging catecholamine transporters. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. Presents catecholamine symposium proceedings Chapters cover a variety of topics such as cellular dynamics of catecholamine release and re-uptake, catecholamines in mood regulation and imaging catecholamine transporter.s With the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.

Table of Contents

Front Cover.
Half Title Page.
Title Page.
Copyright Page.
Contents.
Preface.
Contributors.
1: Catecholamine Biosynthesis, Storage, and Release.
2: Intracellular Stability of Tyrosine Hydroxylase: Phosphorylation and Proteasomal Digestion of the Enzyme.
3: Tyrosine Hydroxylase: Regulation by Feedback Inhibition and Phosphorylation.
4: GTP Cyclohydrolase Regulation: Implications for Brain Development and Function.
5: Brain Neurons Partly Expressing Dopaminergic Phenotype: Location, Development, Functional Significance, and Regulation.
6: Granins and Catecholamines: Functional Interaction in Chromaffin Cells and Adipose Tissue.
7: Interactions of Neuropeptide Y, Catecholamines, and Angiotensin at the Vascular Neuroeffector Junction.
8: Catecholamine Circuits and Brain Function.
9: Neural Circuit Mechanism for Learning Dependent on Dopamine Transmission: Roles of Striatal Direct and Indirect Pathways in Sensory Discrimination.
10: Selective Ablation of Dopamine β-Hydroxylase Neurons in the Brain by Immunotoxin-Mediated Neuronal Targeting: New Insights into Brain Catecholaminergic Circuitry and Catecholamine-Related Diseases.
11: Catecholamine/Serotonin Interactions: Systems Thinking for Brain Function and Disease.
12: The Enduring Centrality of Dopamine in the Pathophysiology of Schizophrenia: In Vivo Evidence from the Prodrome to the First Psychotic Episode.
13: Catecholamine Biomarkers, Gene Therapy, and Drug Discovery.
14: Catecholamine Metabolites Affected by the Copper-Dependent Enzyme Dopamine-Beta-Hydroxylase Provide Sensitive Biomarkers for Early Diagnosis of Menkes Disease and Viral-Mediated ATP7A Gene Therapy.
15: Biomarkers, Mechanisms, and Potential Prevention of Catecholamine Neuron Loss in Parkinson Disease.
16: AADC Deficiency: Occurring in Humans, Modeled in Rodents.
17: Role of Hypoxia and HIF2α in Development of the Sympathoadrenal Cell Lineage and Chromaffin Cell Tumors with Distinct Catecholamine Phenotypic Features.
18: Localization and Expression of VMAT2 Aross Mammalian Species: A Translational Guide for Its Visualization and Targeting in Health and Disease.
19: Catecholamine Receptors: Prototypes for GPCR-Based Drug Discovery.
20: Catecholamines and Stress.
21: Stress-Triggered Changes in Peripheral Catecholaminergic Systems.
22: Neuropeptide–Catecholamine Interactions in Stress.
23: Neuropeptide Regulation of the Locus Coeruleus and Opiate-Induced Plasticity of Stress Responses.
24: Identifying Links in the Chain: The Dynamic Coupling of Catecholamines, Peptide Synthesis, and Peptide Release in Hypothalamic Neuroendocrine Neurons.
25: Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP): A Master Regulator in Central and Peripheral Stress Responses.
Index.