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Introduction to General, Organic and Biochemistry 10th Edition

Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

  • Published
  • Previous Editions 2010, 2007
  • 1008 Pages


This bestselling text continues to lead the way with a strong focus on current issues, pedagogically rich framework, wide variety of medical and biological applications, visually dynamic art program, and exceptionally strong and varied end-of-chapter problems. Revised and updated throughout, the tenth edition now includes new biochemistry content, new Chemical Connections essays, new and revised problems, and more. Most end of chapter problems are now available in the OWL online learning system.

Frederick A. Bettelheim, Adelphi University

Frederick Bettelheim was a distinguished university research professor at Adelphi University and a visiting scientist at the National Eye Institute. He co-authored seven editions of INTRODUCTION TO GENERAL, ORGANIC, AND BIOCHEMISTRY, ORGANIC CHEMISTRY, and several Laboratory Manuals. He is also the author of EXPERIMENTAL PHYSICAL CHEMISTRY and co-author of numerous monographs and research articles. Professor Bettelheim received his Ph.D. from the University of California, Davis.

William H. Brown, Beloit College

William H. Brown is emeritus professor of chemistry at Beloit College, where he was twice named Teacher of the Year. His teaching responsibilities include organic chemistry, advanced organic chemistry, and, more recently, special topics in pharmacology and drug synthesis. He received his Ph.D. from Columbia University under the direction of Gilbert Stork and did postdoctoral work at California Institute of Technology and the University of Arizona.

Mary K. Campbell, Mount Holyoke College

Mary K. Campbell was Professor Emeritus of chemistry at Mount Holyoke College, where she taught biochemistry, general chemistry, and physical chemistry, as well as advised undergraduates working on biochemical research projects. Her avid interest in writing led to the publication of many highly successful editions of this textbook. Originally from Philadelphia, Dr. Campbell received her Ph.D. from Indiana University and completed postdoctoral work in biophysical chemistry at Johns Hopkins University. Her areas of interest included researching the physical chemistry of biomolecules, specifically, spectroscopic studies of protein-nucleic acid interactions. She was also coauthor with Shawn Farrell on BIOCHEMISTRY, 8th Edition (Cengage Learning), as well as several editions of GENERAL, ORGANIC, AND BIOCHEMISTRY by Bettelheim, Brown, Campbell, Farrell, and Torres.

Shawn O. Farrell, Olympic Training Center

Shawn O. Farrell, a native of Northern California, received his B.S. in biochemistry from University of California, Davis, studying carbohydrate metabolism. He completed his Ph.D. in biochemistry at Michigan State University, where he focused on the study of fatty acid metabolism. Dr. Farrell became interested in biochemistry while in college, as it was relevant to his passion for bicycle racing. He raced competitively for 15 years and now officiates bicycle races worldwide. He has taught biochemistry lecture and laboratory courses at Colorado State University for 16 years and now works for USCycling. Professor Farrell has written scientific journal articles about specific research projects and about laboratory teaching, as well as articles for sports publications, such as "Salmon, Trout, and Steelheader" magazine. He is co-author with Mary Campbell on BIOCHEMISTRY, 7e (Cengage Learning).

Omar Torres, College of the Canyons

Omar Torres received his undergraduate degree in Chemistry from Texas A&M University in 1998 and his graduate degree in Inorganic Chemistry from UCLA in 2001. He has experience in teaching, research (inorganic, organic, and analytical) and academic administration. Professor Torres taught both inorganic and organic chemistry at UCLA, where he earned two UCLA Department of Chemistry Awards for Excellence in Teaching for the 1998-1999 and 1999-2000 school years. In addition, Professor Torres has worked at the Dow Chemical Company (Freeport, TX) in the area of Analytical Quality Control, developing and implementing new technologies for various plant operators and analytical scientists. He is currently Dean of Science at the College of the Canyons.
  • Ten percent of the book's problems are new or revised. In addition, all problems in the tenth edition are now available in the OWL online learning system.
  • New "Chemical Connections" boxes such as, "DDT, A Boon and a Curse," "From Moldy Clover to a Blood Thinner," and "Is There a Connection Between Carbohydrates and Obesity?" have been added to the text's more than 150 Chemical Connections essays. End-of-chapter problems associated with "Chemical Connections" are now keyed to provide students with immediate reinforcement.
  • New up-to-date biochemistry coverage includes material on Membrane Cholesterol Function (Chapter 21), Transition Metals and Their Effect on the Structure of Proteins (Chapter 22), Enzyme Inhibitors in Medicine (Chapter 23), Obesity and Type-II Diabetes (Chapter 24), Synthetic Genome (Chapter 26), Nutrient Deficiencies Linked to Depression (Chapter 30), and Immunization (Chapter 31).
  • Coverage of balancing chemical equations now appears earlier in Chapter 4, Chemical Reactions, and the more difficult calculations involving mass relationships have been moved to the end of the chapter.
  • Allotropes of carbon are now included in an expanded Section 5.9, What Are the Characteristics of the Various Types of Solids?
  • Chapter 8, Acids and Bases, now covers the Activity Series.
  • A new "How To" box in Chapter 11 emphasizes the skills students need to master "How to Draw Alternative Chair Conformations of Cyclohexane."
  • Organic mechanisms are now simplified into easy-to-remember steps: add a proton, take a proton away, break a bond, and make a bond in Chapter 12, Alkenes and Alkynes.
  • An enhanced version of the OWL online learning system now includes Interactive Examples from the text and more parameterized end-of-chapter questions that encourage students to practice multiple questions of the same type with different chemicals, wording, and numbers to ensure their mastery of the underlying chemical concepts. In addition, OWL now includes a multimedia eBook, the interactive customizable Cengage YouBook, as well as an optional Solutions Manual eBook.
  • Problem-Solving Strategies: To help students organize the information to solve a problem, each chapter example includes a description of the strategy used to arrive at the solution.
  • Visual Impact: Many illustrations have heightened pedagogical impact. Figures such as Figures 6.4 (Henry's Law) and 6.11 (electrolytic conductance) show the microscopic and macroscopic aspects of a topic under discussion.
  • Chemical Connections: More than 150 essays with photos describe applications of chemical concepts presented in the text, linking the chemistry to their real uses. In addition, application boxes cover diverse topics such as diseases, drugs, and biochemical pathways.
  • Chapter Summaries: At the end of each chapter, restated key questions are followed by summary paragraphs that highlight the concepts associated with the questions.
  • "How To" Boxes: Emphasizing the skills students need to master the material, "How To" boxes cover such topics as "How to Determine the Number of Significant Figures in a Number" (Chapter 2) and "How to Interpret the Value of the Equilibrium Constant, K" (Chapter 7).
  • Superb Art Program: Designed to clarify and teach, the book's art program features annotated illustrations, molecular models, and macro/micro graphics.
  • Key Questions: The text's "Key Questions" framework guides students through each chapter using section head questions that emphasize key chemical concepts.
  • Summary of Key Reactions: Each organic chemistry chapter (10-19) includes an annotated summary of all the new reactions, keyed to sections in which they are introduced. An example of each reaction is also included.
  • Looking Ahead Problems: Chapter-ending "Looking Ahead" problems relate the application of principles in the chapter to material in upcoming chapters.
  • Tying-It-Together and Challenge Problems: These problems build on material presented in earlier chapters, as well as test student knowledge of the material.
1. Matter, Energy, and Measurement.
2. Atoms.
3. Chemical Bonds.
4. Chemical Reactions.
5. Gases, Liquids, and Solids.
6. Solutions and Colloids.
7. Reaction Rates and Chemical Equilibrium.
8. Acids and Bases.
9. Nuclear Chemistry.
10. Organic Chemistry.
11. Alkanes.
12. Alkenes and Alkynes.
13. Benzene and Its Derivatives.
14. Alcohols, Ethers, and Thiols.
15. Chirality: The Handedness of Molecules.
16. Amines.
17. Aldehydes and Ketones.
18. Carboxylic Acids.
19. Carboxylic Anhydrides, Esters, and Amides.
20. Carbohydrates.
21. Lipids.
22. Proteins.
23. Enzymes.
24. Chemical Communications: Neurotransmitters and Hormones.
25. Nucleotides, Nucleic Acids, and Heredity.
26. Gene Expression and Protein Synthesis.
27. Bioenergetics: How the Body Converts Food to Energy.
28. Specific Catabolic Pathways: Carbohydrate, Lipid, and Protein Metabolism.
29. Biosynthetic Pathways.
30. Nutrition.
31. Immunochemistry.
32. Body Fluids.
Find this chapter on the book's companion website. To access, enter ISBN 1-133-10508-4 at
Appendix 1. Exponential Notation.
Appendix 2. Significant Figures.
Answers to In-Text and Odd-Numbered End-of-Chapter Problems.

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